Volume 19, Number 1

Analgesic Potential of Low-Molecular-Weight Peptide Fractions from Central Asian Cobra (<em>Naja Oxiana Eichwald</em>) Venom

Yuldashev Eldor Ilkhomjon Ogli12*Sadikov Erkin Saodatovich1Sultanalieva Nadira Murodovna1Jovlieva Dilfuza Tilovovna2Temirov Abdumovlon Abduvalievich2and Mutalov Karimjan Abdurakhimovich2
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DOI : https://dx.doi.org/10.13005/bpj/3394

Effect of Flavonoids on PTP and Dehydrogenase Activity in Liver Mitochondria

Nurali Ergashev1Boburbek Yuldoshev1*Esokhon Komilov1Mavluda Kenjayeva1Mukhlisa Ikromova2Yulduz Rakhmatillayeva2Hulkar Hazratova2Komila Eshbakova3Doniyor Siddikov³Bakhrom Komilov4Rustam Makhmudov5Muzaffar Asrarov1.
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DOI : https://dx.doi.org/10.13005/bpj/3393

Ethnobotanical Survey of Aromatic and Medicinal Plants Used in Kenitra Province -Morocco

Amina Essamett1*Ilham Rhzali2Nada Belmejdoub1Hefdhallah Alaizari1Mohammed Ennouali1Mohammed Ouhssine1
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DOI : https://dx.doi.org/10.13005/bpj/3392

Assessment of the Anti-Inflammatory Activity of Cu(L-Alanine)₂ in Acute Inflammation Animal Models

Siti Nur Syahida Abdul Jalil1Ng Chin Theng2Fong Lai Yen3Yong Yoke Keong4Muhammad Nazrul Hakim15*Zuraini Ahmad1
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DOI : https://dx.doi.org/10.13005/bpj/3391

Comparative Study of the Pharmacological Properties of Amyrin Compounds Derived from the Composition of Euphorbia <em>Milii:</em> Molecular Docking and SWISSADME Calculations

Mohira Nuraddinova1Akmal Islomov2Arofat Inkhonova3Shukhrat Khakberdiyev4Risolat Norboboyeva5Akmal Khaitov 6and  Nodira Kurbanova7
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DOI : https://dx.doi.org/10.13005/bpj/3390

Evaluation of Neuropharmacological Activities of Different Fractions of <em>Annona </em><em>reticulata</em> Linn. Leaves

Tasnia Binte Bari Kabbo1 Md. Sohel Rana15*Sukanta Deb2Farjana Afrin3Md. Shajalal Reza4Shahriar Mohammad Shohan3and Pritesh Ranjan Dash15*
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DOI : https://dx.doi.org/10.13005/bpj/3389

Optimal Method Selection for Extracting Bioactive Compounds from <em>Prunus spinosa</em> L. Fruits and Evaluating the Antimicrobial Activity of the Resulting Extract

Oksana Barna1Nataliia Aponchuk1Lidiya Romanyuk2Mariia Hrabovets2Mariana Fedorovska3 and Mariia Shanaida4*
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DOI : https://dx.doi.org/10.13005/bpj/3388

Effect of Ramadan Fasting on Chronic Kidney Disease Patients

Hala Sabry Alsaedy1*Ragaa Ramadan Mohamed 1Mai Elsaied Abdelal1Alshaymaa Abd Elbadie Abd Elalim2Eman Refaat  Youness3 and  Ahmed El-Sisi4
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DOI : https://dx.doi.org/10.13005/bpj/3387

Design a Low Cost Device for Preventing Fetal Distress by Analysis of Heart Rate.

Nguetsop Hermann Beaumont1*Jean Mbihi1Gamom Ngounou1and Moffo Lonla2
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DOI : https://dx.doi.org/10.13005/bpj/3386

The Impact of Helicobacter Pylori Infection on Renal and Hepatic Function Parameters in Saudi Arabi, A Case-Control Study

Madyha Hassan Mahmoud1Kamal Upreti2Mohammed Abdullah Jeraiby3Rituraj Jain4*Yahia Mjery1Mahdi Mohammed Alnajai5Fozia Siddiq Otaif1and Mohammad Shane Alam1
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DOI : https://dx.doi.org/10.13005/bpj/3385

Analysis of Hybrid and Benchmark Filters for Enhanced Noise Removal in Ultrasound Signals for Osteoporosis Detection

Tamilselvi Rajendran1*Parisa Beham Mohammed ShanmugapriyaSathiya Pandiya LakshmiNandhineeswariand Gayathri
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DOI : https://dx.doi.org/10.13005/bpj/3384

Antihypertensive Medication Use and Biochemical Outcomes in Primary Care Patients: A Multicenter Study in Kosovo

Fitim Alidema1Irena Kostovska2Arieta Hasani Alidema3 and Lirim Mustafa4*
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DOI : https://dx.doi.org/10.13005/bpj/3383

Effects of 2-Benzoylbenzoic Acid on Viability and Nitric Oxide Production in HIG-82 Synovial Fibroblasts.

Wan Nooremira Wan Rashidi1Nurul Syuhada Nordin1Che Ku Dahlan Daud2Mohd Sofian Omar Fauzee3Zuraini Ahmad1and Muhammad Nazrul Hakim14*
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DOI : https://dx.doi.org/10.13005/bpj/3382

Synthesis and Antidepressant Activity of 5-(2-Aminophenyl)-1,3,4-Oxadiazole-2-(3H)-Thione

Zafar Isomiddinovich Sanoev14Sokhib Zamon ogli Rashidov14Tolmas Tolibovich Khamroev14*Ibrokhimjon Tuychievich Abdinazarov15Sukhrob Davlatyor ogli Rakhimboev2Dilnoza Safaralievna Ismailova3Burkhon Zhuraevich Elmuradov3and Madina Aladdin kizi Shakhmurova4
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DOI : https://dx.doi.org/10.13005/bpj/3381

External Validation of PET Radiomics-Based ML Model for Non-Invasive Lung Cancer Subtype Classification

Pooja Dwivedi12Sagar Barage2*Ashish Kumar Jha3Archi Agrawal13and Venkatesh Rangarajan13
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DOI : https://dx.doi.org/10.13005/bpj/3380

Generative Adversarial framework for CT image denoising using Self-Attentive Residual UNet and Patch GAN Discriminator

Swapna Katta1Prabhishek Singh2*Deepak Garg1and Manoj Diwakar3
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DOI : https://dx.doi.org/10.13005/bpj/3379

Effects of<em> Raw </em>Materials from<em> Green Fenugreek </em>and<em> Black Mulberry </em>on Oxidative Stress Biomarkers Induced by Carbon Tetrachloride Toxicity in Experimental Rats

Lobna Saad Mohammed Abd Elmeged12*Ali Khalaf Ahmed Albaggar3
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DOI : https://dx.doi.org/10.13005/bpj/3378

Role of F-4 Isoquinoline Alkaloid, Dihydroquercetin Flavonoid and Conjugate DKV-6 in Myocardial RyR2 and SERCA2a under Normal and Hypoxic Conditions.

Sadriddin Nurillo ugli Boboev1.3*Inoyat Zulfiqorovich Zhumaev1Pulat Bekmuratovich Usmanov1Abdisalim Abdikarimovich Zaripov1Shavkat Yusubovich Rustamov1Shakhnoza Bakhtiyorovna Qurbonova1Eldor Bakhtiyor ugli Ibragimov1Sardor Bakhtiyor ugli Sobirov1Sherzod Niyatqobulovich Zhurakulov2 .
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DOI : https://dx.doi.org/10.13005/bpj/3377

A laboratory Study on the Most Important Tests for COVID-19 Patients and their Interrelationships

Aleem Mardas Khudhair1Abbas Razzaq Abed1*and Ibtisam Mohammed Hussein2
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DOI : https://dx.doi.org/10.13005/bpj/3376

Quantification of Dabigatran in Spiked Plasma, Bulk and Formulation Using 1 – Naphthol as Per ICH Guidelines by UV Visible Spectrophotometer

Khagga Bhavya Sri1*Thandra Ambika1and Dhilli Rao Gorja2
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DOI : https://dx.doi.org//10.13005/bpj/3375

Molecular Detection of <em>Helicobacter pylori </em>and Epstein-Barr Virus Co-infection among Sudanese Gastritis Patients, Khartoum State- Sudan

Hind Haidar Ahmed1*Israa Elshayeb Ali Mohamed1Mutaz Fathelrahman Saad1Samar Mohammed Saeed1Wafaa Mohammed Abdalla1Ahmed Bakheet Abd Alla2May Mohamed Ali3Tagwa Salah Ahmed24and  Mohammed Siddig Abd Elaziz5
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DOI : https://dx.doi.org/10.13005/bpj/3374

Correlation Between Regulator T Cell Levels and Acetylcholine Receptor Antibody Levels and Clinical in Patients with Myasthenia Gravis

Elta-Diah Pasmanasari*William TanyawanDodik-Tugasworo PramukarsoRetnaningsih RetnaningsihJimmy-Eko-Budi HartonoSuryadi Suryadi
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DOI : https://dx.doi.org/10.13005/bpj/3373

Effects of Melatonin-Rich Extract from Red Beans (<em>Phaseolus Vulgaris</em> L.) on Glucose Levels and GLUT4 Gene Expression in Diabetic Rats

Yanuarita Tursinawati1*Lukman Faishal Fatharani 1Amin Samiasih2Ardita Nadia Zahirah3Shafa Noor Aulia3and Ahmad Reihanzaki3
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DOI : https://dx.doi.org/10.13005/bpj/3372

Medicinal Plants Used by Women in Morocco's Settat Region for Gynecological and Dermatological Care

Milouda Chebabe1*Khaddouj El Goundali1Aslaou Fatima3 Kawtar Chafik12Lalla Asmaa Katir Masnaou1Msatfa Nabila1Ibrahimi Halima2Latifa Mochhoury1
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DOI : https://dx.doi.org/10.13005/bpj/3371

Determination of the Simultaneous Hepatoprotective and Antidepressant Activity of the Composition Hepalipin and Yantacin

Abdumalik Nigmatovich Aripov1Lola Lazizovna Akhunzhanova1Orifzhon Abdumalikovich Aripov1and Tolmas Tolibovich Khamroev123*
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DOI : https://dx.doi.org/10.13005/bpj/3370

Integrative Genomic and Genotype-Phenotype Analysis of a Homozygous PIGQ Frameshift Variant in MCAHS4

Yousef Al-Hajaya
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DOI : https://dx.doi.org/10.13005/bpj/3369

Proliferative and Protective Effects of <em>Vetiveria zizanioides</em> on Obesity and Male Fertility In Wistar Albino Rats

Sangeetha Raja1Satyajit Mohapatra2Kalaivani Amitkumar3Kasthuri Natarajan4*Jamuna Rani1Alwin Devasagayam5and Farhana Rahman6
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DOI : https://dx.doi.org/10.13005/bpj/3368

Anti-Chikungunya and Anti-Inflammatory Therapeutic Potential of <em>Cynodon dactylon</em> Aqueous Extract

Kumari Soniya1Sanjit Boora1Suman Yadav1Abhishekh Kumar Bharti2Manisha Sharma1Poonam Patil2Kalichamy Alagarasu2Deepti Parashar2 and Samander Kaushik1*
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DOI : https://dx.doi.org/10.13005/bpj/3367

Computer-based Screening of Compounds in the Traditional Chinese Medicine Database to Specify a Prospective Inhibitor of the New Delhi metallo-β-lactamase-1

Hasanain Abdulhameed Odhar
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DOI : https://dx.doi.org/10.13005/bpj/3366

Low Serum Vitamin D And Insulin Like Growth Factor-1 (IGF-1) Level as Risk Factors for Hypertension Among Older Adults

Luh Putu Ratna Sundari1*I Dewa Ayu Inten Dwi Primayanti1I Ketut Tunas2Made Alyashanti Radya Bulandari3
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DOI : https://dx.doi.org/10.13005/bpj/3365

Differential Oxidative Susceptibility Between Metabolically Healthy and Unhealthy Obesity

Khalid Mohammad. Abu Khadra1*Mohamed Izzat. Bataineh1Rania Khalid. Abu-Khadra2Jumana Saleh3
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DOI : https://dx.doi.org/10.13005/bpj/3364

Type 2 Diabetes Mellitus Detection using Heterogeneous Machine Learning Models: A Cross-sectional Study

Shruthi Mittemari Lakshminarayan Jagannath12*Nishita Nitin Joshi12Tanushree Giridharan12Nirmala Devi Manickam1
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DOI : https://dx.doi.org/10.13005/bpj/3363

Molecular Patterns of Beta-Thalassemia in Taif Province- Saudi Arabia: Determination of Prevalent genotypes and Regions with High Incidence<strong> </strong>

Tariq Elfatih. Elmissbah1Hayaa Moaid. Huthali1Mamdouh Allahyani1Amal Shuwman Alosaimi1and Heba Mohammed. Elmasry2
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DOI : https://dx.doi.org/10.13005/bpj/3362

In silico Pharmacokinetics and In vivo Anti-inflammatory Activity of C-4 Composition

Lazizbek Makhmudov1*Nigora Tagayalieva1Izzatullo Abdullaev1Ulugbek Gayibov1Kuzijon Baratov1Sherzod Usmonov1Gulnora Rakhmonova1Rano Yaqubova1Natalia Vypova1and Shaira Karimova2
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DOI : https://dx.doi.org/10.13005/bpj/3361

Phytoconstituents and Molecular Docking of Ethanol Extract of <em>Sargassum aquifolium</em> J. Agardh with Different Apoptosis Proteins Involved in Hepatocellular Carcinoma

Anak Agung Ayu Putri Permatasari1*Putu Angga Wiradana1I Gede Widhiantara1Ni Kadek Yunita Sari1I Made Gde Sudyadnyana Sandhika1Mochammad Aqilah Herdiansyah2Win Darmanto2 and Novaria Sari Dewi Panjaitan3
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DOI : https://dx.doi.org/10.13005/bpj/3360

Scorpi-XStack: Improving Type 2 Diabetes Prediction via Feature Optimization and Stacking

Usha Velusamy1*Sathya Velusamy2 Anitha Thambiayyan3Sathiya Priya Selvaraj4Vinodhini Kanakaraj1and Madhumitha Chidambaram1
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DOI : https://dx.doi.org//10.13005/bpj/3359

Study of Peptidic HIV-1 Protease Inhibitors Based on Pharmacokinetics, Site Selectivity, Intermolecular Interaction and Energy Parameters

Swati1 Iffat Azim2Akhilesh Singh3Anil Kumar Soni4Vishnu Kumar Sahu56*
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DOI : https://dx.doi.org/10.13005/bpj/3358

Interpretable Machine Learning for Heart Disease Risk Assessment: Leveraging SHAP Values to Identify Clinically Actionable Predictors

Bhupesh Rawat12Himanshu Pant12 and Ankur Bist32
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DOI : https://dx.doi.org/10.13005/bpj/3357

Green Fabrication of <em>Pergularia daemia-</em>Mediated Silver Nanoparticles for Antioxidant and Hepatocellular Carcinoma Applications

Renuka SaravananSivakumar Ramalingam*
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DOI : https://dx.doi.org/10.13005/bpj/3356

Cerebrospinal Fluid Profile in Patients with Suspected Viral Meningitis at Tertiary Infectious Disease Hospital in Jakarta

Maria Lawrensia Tampubolon1. Edith Nadya Apriliani2. Daniel Joko Wahyono2.Siti Maemun34*
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DOI : https://dx.doi.org/10.13005/bpj/3355

Polyphenolic Profile and Multimodal Biological Activity of <em>Ajuga turkestanica</em> Extract: From In vitro Antioxidant Potential to In vivo Antihypoxic Protection

Sabina Gayibova1*Galiya Nasyrova1Gulnora Rakhmonova1Mamura Sabirova1Dildora Abduazimova1*Elena Nikitina2Olga Verushkina3 and Eva Ivanišová4
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DOI : https://dx.doi.org/10.13005/bpj/3354

Targeting Quorum Sensing to Combat Multidrug Resistance: A Molecular Dynamics Study of Acridine-Sulfamethoxazole Hybrids

Magesh Mohan1 Renukadevi Jeyavelkumaran2* Sanjay Valliappan2 Sri Vaishnavi Velegatla2 Shakthi Harikrishnan2Kadir Aravindan2and  Balaji Ravikumar2
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DOI : https://dx.doi.org/10.13005/bpj/3353

Acetogenin-Rich <em>Annona muricata</em> Leaf Extract as a CDK6 Inhibitor and E2F2 Suppressor in MCF-7 Breast Cancer Cells

Aryo Tedjo12*Novi Yantih3Fadilah2and Mohamad Rafi4
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DOI : https://dx.doi.org/10.13005/bpj/3352

LC-MS Based Metabolomics,<em> In vitro</em> and <em>In silico </em>Approaches to Characterize Possible Inhibitors of Alpha-glucosidase and Protein Glycation from <em>Premna serratifolia</em> L: Implications in Controlling Diabetes

Sagar Bhayye1Rakhee Dangi2*and Sagar Datir3
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DOI : https://dx.doi.org/10.13005/bpj/3351

Early-Stage Diabetes Prediction Using a Stacked Ensemble Model Enhanced with SHAP Explainability

Shahnawaz Ahmad1Shahadat Hussain2Mohd. Arif3*and Mohd. Aquib Ansari3
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DOI : https://dx.doi.org/10.13005/bpj/3350

Lesion-Aware Ordinal Transformer for Diabetic Retinopathy Classification from Fundus Images

Ambuj Kumar Agarwal1*Abu Bakar Bin Abdul Hamid2Danish Ather3Raj Gaurang Tiwari4Indrajit De5and Kunchanapaalli Rama Krishna6
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DOI : https://dx.doi.org//10.13005/bpj/3349

Label-free Classification of MCF7 and HeLa Cells using High-content Imaging and Deep Learning

Shagun Sharma12Kalpna Guleria2*Ayush Dogra3Monika Sharma4and Satyam Kumar Agrawal4
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DOI : https://dx.doi.org//10.13005/bpj/3348

Molecular Docking and DFT-Based Evaluation of Pyridine-2-Carbothioamide First-Row Transition-Metal Complexes Targeting Topoisomerase IIα

Mehribon Pirimova12*Masud Karimov2 Djalilov Abdulahat2Feruz Ismoilov2Muparrax Xodjayeva1Oybek Sultonov2Shokhida Keldiyorova3and Muhammad-Ali Mustafaev2
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DOI : https://dx.doi.org/10.13005/bpj/3347

Lactate Dehydrogenase and Biochemical Markers as Indicators of Treatment Response in Breast Cancer

Rania Kadhim1Emad Yousif1*Suhad Ibrahim1and Muna Bufaroosha2
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DOI : https://dx.doi.org/10.13005/bpj/3346

A Comprehensive Review on the Importance of Clinical Trials and Their Advancements in Drug Development and Healthcare

Raj Kumar Devarakonda
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DOI : https://dx.doi.org/10.13005/bpj/3345

Human Metapneumovirus (HMPV): Epidemiology, Pathogenesis, Clinical Impact, and Advances in Diagnosis, Treatment, and Vaccine Development

Alankar Shrivastav1*Monika Singh2Tribhuwan Kumar Vashishtha1Rajat Saxena1Arun Kumar Mishra1and Navneet Verma1
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DOI : https://dx.doi.org/10.13005/bpj/3344

Global Research Trends in Machine Learning and Scoring Systems for Drug-Resistant Tuberculosis Outcome Prediction: A Bibliometric Analysis

Farida Murtiani12*Mondastri Korib Sudaryo3Evi Martha4Diah Handayani56Helwiah Umniyati7Annisa Ayu Lestari3Bada Febriyani3Fatimah Fatimah3and Amelia Marisa3
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DOI : https://dx.doi.org/10.13005/bpj/3343

Harnessing Phytoactive Compounds for Targeting Neuroinflammation and Inflammatory Receptors: A Polypharmacology Approach Integrating Molecular Dynamics Simulations and In Silico Formulation Design

Ranajit NathRajesh Ephraim Jesudasan*
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DOI : https://dx.doi.org/10.13005/bpj/3342

The Ancient Practice of Oil Pulling: A Comprehensive Guide to Oral Health

Roma MascarenhasShreya Hegde*
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DOI : https://dx.doi.org/10.13005/bpj/3341

Survival Rate of Chronic Kidney Disease (CKD) Patients Undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD): A Meta-Analysis

Yenny Kandarini1*and I Made Adi Narendranatha Komara2
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DOI : https://dx.doi.org/10.13005/bpj/3340

A Comprehensive Review on the Immune System and Immune Therapy in Liver Cancer and Colorectal Cancer

Faruk Alam1Alindam Ghosh21Arpan Sen23Debraj Dey2Soumya Sunder Ghora2Saurav Guchhait2Pakhi Pandey2. Avik Dutta21*and Prithviraj Chakraborty3
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DOI : https://dx.doi.org/10.13005/bpj/3339

Advanced AI-Based Early Warning Framework for ICU Patient Monitoring Using Temporal Clinical Data

Mohammad Maroof Siddiqui
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DOI : https://dx.doi.org//10.13005/bpj/3338

Nutraceuticals: Recent Advances, Therapeutic Potential, and Future Directions – A Comprehensive Review

Paravastu Venkata Kamala Kumari*Penumetcha Sindhura Devi
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DOI : https://dx.doi.org//10.13005/bpj/3337

Navigating the Maze: A Comprehensive Review of Systemic Lupus Erythematosus

Umesh Laddha*Aishwarya LadPravin PawaraPrashant AdhavJanhavi GanoreChanchal PagarSanjay Kshirsagar
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DOI : https://dx.doi.org/10.13005/bpj/3336

Dietary Patterns and Intermittent Fasting as Modulators of the Oral Microbiome and Periodontal Inflammation: A Narrative Review

Sameena Parveen1*Mohammed Mousa Hassan Bakri1Samar Saeed Khan1Swetha Vempalli1Reghunathan S.Preethanath2Mohammed Nazish Alam2Mohamed Hamdi Mansy2Hind Ali Osman2Husham E. Homeida1  Ahmed Mostafa Ahmed Mostafa1and Solima Ibrahim Yagoob3.
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DOI : https://dx.doi.org/10.13005/bpj/3335

Pharmacology of Atenolol: A β<sub>1</sub>-selective Adrenoceptor Inhibitor

Mohammad Shah Amran1*Nasrin Akhter1Fareha Anan Shristy2Sumaiya Rahman1Runa Akter1and Mohammad Josim Uddin1
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DOI : https://dx.doi.org/10.13005/bpj/3334

The Therapeutic Potential of Novel Drug Targets in Metabolic Disorders- A Review

Ravinesh MishraManju Jakhar*Rajeev DhimanLaraib KhanAditya RajVandana DeviAnjali Kumari Ajay Kumar
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DOI : https://dx.doi.org/10.13005/bpj/3333

Preclinical Evaluation of Antiarrhythmic Drugs Against Atrial Fibrillation in Experimental Animal Models.

Mayram Miralievna Boltaeva1Zafar Isomiddinovich Sanoev27Tolmas Tolibovich Khamroev27*Ravshan Komiljonovich Sultonov3Sirojiddin Rashidovich Kenjaev4Nilufar Makhsudovna Dushaeva5Bakhtiyor Bakhodiro’g’li Abdurasulov6Odinakhon Ubaydullaevna Ikramova6Qobiljon G’ofirjono’g’li Sobirov6Abduqodir Abdurashidovich Qobulov6 and Sokhib Zamonogli Rashidov27
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DOI : https://dx.doi.org/10.13005/bpj/3474

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