Habibeh zare

Department of Biology, Payame Noor University, Bushehr Iran.

Abstract

This study is examined the role of alkaloids in pharmacist plant (Physalis alkekengi) and equilibrium of alkaloids in various growth parts of leaves, stem, root and production parts of fruit. Effective factors mingled in synthesis of alkaloids, that the most important of them is reading of amino acids (like phenyl alanine, triozin, lycin, triptophan) and also towart and matasion. The most important alkaloids are like morphins, codeins and afdrin. For searching alkaloids one can used Mayer and Dragendorff introducer in one percent acid solution of coloridric acid. The amount of production in root is measured more than that in fruit and leaves.

Keywords

Natural products; Total alkaloids; Physalis alkengi

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Copy the following to cite this article: Zare H. Amount of Natural Products and Total Alkaloid Substances in Fruit, Root and Leaves of Physalis Alkekengi. Biomed Pharmacol J 2010;3(1)

Copy the following to cite this URL: Zare H. Amount of Natural Products and Total Alkaloid Substances in Fruit, Root and Leaves of Physalis Alkekengi. Biomed Pharmacol J 2010;3(1). Available from: http://biomedpharmajournal.org/?p=1123

Introduction

Scientific name

Physalis alkekengi. L (Solanaceae)

Physalis is a grassy plant with 20-60 cm height that grow wildly on calcaluous grounds of European areas and some parts of Asia like Iran.

Growth characteristics of this plant is a stem with sharp- pointet elliptical periodical leaves and long fail leaves. And its production characteristic is that their flower appear during khordad or shahrivar. They have single position on the stem and have a short fail flower on the head. Pistil consists of a two- space ovary and after ripening the fruit be come red and it is fenced in ared screen. This screen resulted from growing and joining of flower cup.

Chemical chompositions

The fruit of this plant have some kinds of acids like ascorbic a cid , citric acid and sugar. A bitter alkalodian material named physaline is found in its fruit, leave and root. It is noted that the amount of vitamin C in the fruit of this plant is 2 times of limon juice.

Curing properties

The fruit of this plant has medromeline impact its leaves, stem and flower cup aremong strong bitter and blood filteration medicines. It can reper urine acid and urine sediments (calcium aurat and acsalafes). It is extracted asubstance named cryptoxanthin from it is fruit and flower that is a colorful cartonoidic material with similar effect of vitamin A.

The role of alkaloids in plant

Alkaloids play on important role in maintaining of plant. Because they have bitter taste and are of then touix. Herbivorous animals avoid of consuming it and they are immune of pathogens and insects. They impact on control of plants growth and they are growth regulating factors. They cause destroying of superfluous materials that have azote like uric acid and is added to it. Resulting solution place in a shaker for 2 hours. This solution clarified by a multilayer clean cloth under its system. After that they were put in a 50-60 c bon marry. Then it was sent out and the volume of solution was reche to 15cc by colorform. Then with 15 ml tartaric acid in decounter we extract 2%  alkaloid solution. Then we alkalize it by 25% solution of ammonia uneer air cleaing system and keep constant its ph=9. again solution was reched to 20 ml by colorform and colorform was evaporated in water bath.

Finding

With due to attention to that alkaloids make milk white and orange sedimens invicinty of mayer and dragendroff introductrs, they are used to define the existence of alkaloids in various parts of physalis alkekengi. Total amount of alkaloids in proportion to ML in 5 used sample is obtained. The with calculating by proportion percentage amount of alkaloids which is existent in each part is obtained 15 cc glacial acefic acid is added to each earlen and put for 10 minutes to allow alkaloids to become dissolved in it. Then 3 drops of crystal and ule introducer are added to each earlen. And they titrate with 0/05 normal percoloric acid after titeration the color of crystial and ule convert from violet to blue or green.

Conclusion

Uric that are harmful plant.

Physical characteristics of alkaloids

Alkaloids are often odourless and colorless and they are bitter and unevapovated. Some of them are colorful like kelshicine that is yellow and kanadine that is orange.

Effective factors and materials in synthesis of alkaloids

Various factors effect on synthesis of alkaloids that among them readiness of Aminoacids like (fenelalonine, Tyrozini tryptophan), geographical situation in heritance and mutation are important.

Pharmacological properties of alkaloids

Some of alkaloids like morphin and codoeen are soporific, anti coyghing and antipian. Some others like sterkin and brousins are inciter of central nervous system. Some of them like efedrin cause high blood pressure. In general , alkaloids have extended physiological effects on various nervous of human and animals body.

Materials and methods

For searching alkaloids we can use meyer and dragendorff introducer to distinct the existence of alkaloids in acid solution( with 1% coloridric acid) their existence is proven by forming sediment.

Method of measuring and extracting alkaloids as whole.

First , if is mixed 5 gram of leave , stem , fruit and roots powder with 25 ml solution of ammonia in an erlen. After 1 H 5 minutes 3.ml chloroform  measurement of pharmaceutical effects of colocynths extract on uleppo boil lesion in human.

References

1. Mur E, Schennach H, Schroecksnadel K, Wirleitner B, Winkler C, Fuchs D; In vitro Effects of Two Extracts and Two Pure Alkaloid Preparations of Uncaria tomentosa on Peripheral Blood Mononuclear Cells. Planta med 2004; 70: 205-210.
2. Huang SL, Tsai HL, Duch PD, Yen GC2003;.Prooxidative properties offlavonoids in human lymphocytes. Biosci Biotechnol Biochem.; 67(6): 1215-22.
3. George F, Zohar K, Harider PSM, Klaus B2002; The biological action of saponins in animal system: a review. British Journal of Nutrition; 88: 587-605.
4. Spelman K, Burns J, Nichols D, Winters N, Ottersberg S, Tenborg M2006; Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators. Altern Med Rev.; 11(2)L 128-50.
5. Schwarz E, Metzler J, Diedrich JP, Freudenstein J, Bode C, Bode JC2002; Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate the nonspecific immune response in healthy young men: results of a double-blind, placebo-controlled crossover study. J Immunother.; 25(5): 413-20.
6. Maatooq GT, El-Sharkawy SH, Afifi MS, Rosazza PN1997 ; C-p-Hydroxybenzoyl glycoflavones from Citrullus colocynth. Phytochemistry; 44(1): 187-190.
7. Harborne JB. Phytochemical Methods. 2th ed. Chapman and Hall, London, 1984; 120-128, 192-202.
8. Karumi Y, Onyeyili PA, Ogugbuaja VO2004, Identification of active principles of M. balsamina (Balsam Apple) leaf extracl. Journal of Medical Sciences; 4(3): 179-182.
9. Diwan FH, Abdel-Hassan IA, Mohammed ST2000; Effect of saponin on mortality and histopathological changes in mice. Eastern Mediterranean Health Journal; 6(2/3): 354-351.
10. Shan BE, Yoshida Y, Sugiura T, Yamashita U1999. Stimulating activity of Chinese medicinal herbs on human lymphocytes in vitro. Int J Jmmunopharmacol.; 21(3): 149-59.

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