Nikakhlagh S, Taiebi S, Karampur L. S, Neisi G, Saki N. The Outcome of Endoscopic Surgery on Patients with Sinonasal Inverted Papilloma: A 10 Years Experience. Biomed Pharmacol J 2015;8(October Spl Edition)

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Soheila Nikakhlagh¹, Sana Taiebi², Leila Sistani Karampur², Ghasem Neisi³ and Nader Saki^1*

¹Head and Neck Surgery, Hearing & Speech Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ²Hearing & Speech Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ³Resident of Radiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

DOI : https://dx.doi.org/10.13005/bpj/778

Abstract

Inverted papillomas comprises 0.5-4% of benign epithelial nasal tumors that arise primarily from the lateral nasal wall. The main characteristic is its tendency to recur and the risk of malignant transformation. The present study aims to analyze and report the findings of our team in the treatment of these lesions, especially through the endoscopic approach and the outcomes of the patients. This is a retrospective study describing 38 patients who underwent endoscopic excision or open surgery from March 2001 to March 2012. The patients were studied by age, sex, origin of lesion, presenting symptoms, radiological studies, clinical staging, method of treatment, follow up, surgical outcome, tumor recurrence and associated malignancy. The mean follow-up was 48 months. There were 30 men and 8 women with the mean age of 49.76 years ranging 18 to 78 years old. The most common clinical symptoms were unilateral nasal obstruction (94 .7 %) and rhinorrhea (36.84 %). Disease recurrence rate was 5.3 %. Endonasal endoscopic resection was performed in 32 patients (84.2%), combined approaches were used for 5 patients (13.2%) and external approach only was done in one patient. The most common involvement location was the maxillary sinus (89 %). The ethmoid sinus and the lateral nasal wall were involved in 68% and 55.2% of the cases, respectively. Malignant transformation was observed in 2 patients (5.3 %). Long-term follow up of inverted papilloma is necessary for early detection of recurrence and to allow for surgical salvage. Surgeon’s experience plays a crucial role in the selection of an appropriate method.

Keywords

inverted papilloma; endoscopic surgery; open surgery; outcome