eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2016-08-21 9 2 885 888 10.13005/bpj/1025 8123 article S. Leena Sankari 1 R. Jayasri Krupaa 1 G. M. Kailash Kumar 1 N. Balachander 1 Department of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai - 6 Matrix metalloproteinase are calcium dependant zinc containing endopeptidase  which play important role in  the degradation of extra cellular matrix . MMP play major role in cell proliferation , migration , differentiation , apoptosis .Role of MMP in vascular remodeling is also significant. MMP are involved in various diseases such as matastsis of cancer, athroma , arthritis, and tissue ulceration MMP inhibitors have potential therapeutic value in various diseases. https://biomedpharmajournal.org/vol9no2/mmp-matrix-metalloproteinase/ metalloproteinase arecalcium  proliferation migration