eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2016-08-21 9 2 823 826 10.13005/bpj/1009 8090 article Aravindha Babu 1 L. Malathi 1 R. Karthick 1 S. Leena Sankari 1 Dept of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai-600100. Dental caries is the mostwidespread diseases in humans. In modern times, it has reachedepidemic proportions. Dental caries is a microbiologicinfectious disease of the teeth that endsin localized dissolution and destruction of the calcified structure of the teeth. Dental caries is a multifactorialdisease that is caused by thehost, agent, and environmental factors. The time factor is significantfor the initiation and progression of dental caries. A wide group of microorganisms is established from carious lesions. S.mutans, Lactobacillus acidophilus, and Actinomycesviscosus are the main pathogenic species involved in the inception and development of dentalcaries. https://biomedpharmajournal.org/vol9no2/immunology-of-dental-caries/ dental caries streptococcus mutans Glucosyltransferase