eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2016-04-28 9 1 201 208 10.13005/bpj/927 6620 article Zahra Jallilian 1 Parisa Ziarati 2,3 Pharmacy Faculty, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran –Iran Young Researchers and elite Club, Pharmaceutical Sciences Branch, Islamic Azad University, (IAUPS), Tehran, Iran. Department of Medicinal chemistry, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran –Iran The efficacy of various plants in eliminating different heavy metal contaminants, particularly Lead and Cadmium is a major concern nowadays due to the vast soil pollution in many countries around the world especially Iran. In this research determination of the potential ability of dried aerial parts of  Ferulago Angulara   in companion of black  tea residue  for cleaning up contaminated soil and their probable capability of adsorption  different heavy  metals (Nickel, Lead and Cadmium) was investigated. F. Angulara  were collected in August 2015 from Kermanshah  Province, Iran and samples was identified by the Herbarium of Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS).The contaminated  soil by Ni, Cd and Pb  was put into the   sites  in a way that F. Angulara  and tea leaves residue   were mixed in different percentages up to  20%-20% (W/W)  in examined soils individually and  both of plants together in order to find the effect of companion residues  in possible potential biosorption . Metal contents were detected by Atomic Absorption Spectrophotometer by wet digestion method in every 10 days during 60 days in Research Laboratory. Results indicated that the rate of heavy metals uptake by F. Angulara  is significantly affected by the presence of dried  tea leaves residues (p<0.003 ) . Tea leaves are more capable in absorbing nickel than F. Angulara  and when we put  both together in 20%-10% (tea leaves/ F. Angulara)  the potential of taking up nickel significantly enhanced (p<0.01 ) .The Cadmium and Lead uptake rates by F. Angulara areal parts  are significantly affected by pH and companion in the contaminated soil  (p<0.001). The results of this research concluded that F. Angulara  and  tea residue  in the contaminated  soil have suitable ability for adsorption method and removing  more Lead and Nickel  in pH <7 after 20-60 days of study. https://biomedpharmajournal.org/vol9no1/high-potential-of-ferulago-angulate-schlecht-boiss-in-adsorption-of-heavy-metals/ Biosorption  Ferulago Angulara   Tea leaves residue Heavy metals