eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2016-04-28 9 1 09 13 10.13005/bpj/902 6769 article Al-Shara Mohammad 1 Faculty of Nursing, Irbid National University Irbid, Jordan The present study was conducted to investigate antimicrobial susceptibility pattern of Escherichia coli strains isolated from clinical specimens of Jordanian pediatric patients during a five year period 2005-2009. A total of 2259 E. coli strains were isolated from different clinical specimens and tested for their susceptibility to commonly used antimicrobial agents. Overall, high susceptibility rate was observed for nitrofurantoin (90.4%), followed by ciprofloxacin (85.6%), norfloxacin (83.9%), cefotaxime (83.7%), ceftriaxone (82.4%), and gentamicin (80.8%). Lower susceptibility rates were observed for ampicillin (19.8%) followed by amoxicillin-clavulanic acid (26.8%) and cotrimoxazole (31.6%), Nitrofurantoin was highly effective for E. coli with susceptibility rate of 90.4%. In contrast, ampicillin, amoxicillin-clavulanic acid and cotrimoxazole were found to be ineffective at in vitro for inhibition of the E. coli of pediatric origin. https://biomedpharmajournal.org/vol9no1/antimicrobial-susceptibility-of-escherichia-coli-isolates-from-clinical-specimens-in-children-over-a-5-year-period-in-jordan/ Antimicrobial resistant Escherichia coli pediatric patients