eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-10-25 8 October Spl Edition 91 97 10.13005/bpj/656 4273 article R. Jayaprakash 1 Aruna Sharma 1 N. Aravindha Babu 2 Tagore dental college and hospital Sree Balaji Dental College and Hospital, Bharath University , Chennai. Chewing gums are mobile drug delivery systems. It is a potentially useful means of administering drugs either locally or systemically via, the oral cavity. The medicated chewing gum has through the years gained increasing acceptance as a drug delivery system. Several ingredients are now incorporated in medicated chewing gum, e.g. Fluoride for prophylaxis of dental caries, chlorhexidine as local disinfectant, nicotine for smoking cessation, aspirin as an analgesic, and caffeine as a stay alert preparation. MCGs are solid, single dose preparations with a base consisting mainly of gums that are intended to be chewed but not swallowed. They contain one or more active substances which are released by chewing and are intended to be used for local treatment of mouth diseases or systemic delivery after absorption through the buccal mucosa. https://biomedpharmajournal.org/vol8octoberspledition/therapeutic-chewing-gums-review/ Therapeutic Chewing gums mobile drug delivery systems