eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-10-25 8 October Spl Edition 195 200 10.13005/bpj/674 3945 article Aravindhan T Ranganathan 1 Bagavad Gita 2 J. Bhuvaneshwarri 2 Department of Periodontics, Tagore Dental College, Rathinamangalam, Chennai Department of Periodontics, Sree Balaji Dental College & Hospital, Bharath University, Chennai-600100 Removal of the plaque biofilm mechanically forms the mainstay in the management of periodontal diseases. Mechanical debridement has its inherent limitations and frequent use of antibiotics is essential for complete resolution of the lesion. Antibiotics, when used directly into the site have more advantages than when administered systemically. This review highlight the rationale and beneficial effects of locally delivered agents.   https://biomedpharmajournal.org/vol8octoberspledition/role-of-local-drug-delivery-agents-in-the-treatment-of-periodontal-diseases/ Periodontitis Root planing antibiotics