Veerasamy J. S. M, Raj L. S. M, Sankari S. L, Anitha. Massive Osteolysis of oral cavity: A Review with Emphysis on its Etio-Pathogenesis and Histological Appearance. Biomed Pharmacol J 2015;8(October Spl Edition)

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Published online on: 19-01-2016

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Jai Santhosh Manikandan veerasamy¹, L. S Makesh raj¹, S Leena Sankari², Anitha²

¹Tagore Dental College and Hospital, Rathinamangalam, Chennai ²Department Of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath University , Chennai.

DOI : https://dx.doi.org/10.13005/bpj/644

Abstract

Massive osteolysis is a rare condition of unknown aetiology resulting in progressive destruction of bony structures. Literature reviews suggest less than 40 cases of massive osteolysis in the jaws has been reported.Clinically it is seen mostly between age groupof 18-40 years and depending on the site of involvement is shows various clinical presentation. Even after so many advances in the field of medicine still this disease is still considered as nightmare for the pathologist as the course of the diseaseand prognosis after treatment are unpredictable. As its name indicates its radiological features varies from slow resorption of affected bone finally resulting in complete loss of affected bone.No specific treatment is proven effective against this disease. Hence the purpose of this review is to provide comprehensive in depth idea about the disease to help in early diagnosis.

Keywords

massive; osteolysis; bone disease; vanishing; bone; disease