eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-10-25 8 October Spl Edition 393 401 10.13005/bpj/710 3732 article T Manigandan 1 VT Hemalatha 2 Research scholar and Professor, Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, India Research scholar and Reader, Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, India Oral leukoplakia [OL] is a relatively common oral lesion that which can undergoes malignant transformation. The aim of this review was to assess the effectiveness of treatments for leukoplakia. A medline search from 1983 to 2014 was conducted. The topical or systemic nonsurgical treatments or combination of both was reviewed. https://biomedpharmajournal.org/vol8octoberspledition/insight-of-various-medical-management-of-oral-leukoplakia/ Oral leukoplakia premalignant lesion beta carotene retinoids green tea spirulina lycopene photodynamic therapy acitretin Vitamin A C E Fenretinide Bleomycin celecoxib