eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-10-25 8 October Spl Edition 245 247 10.13005/bpj/684 3934 article M. Rathinavel Pandian 1 Ashish. R. Jain 1 Ragavendra Jayeshc 2 Narasimman. M 1 R. Pradeep 1 Department of Prosthodontics, Tagore Dental College and Hospitals,Chennai, India. Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath University, Chennai-600100 The use of artificial bone graft substitutes has increased as the surgical applications widen and the availability of allograft bone decreases. The ideal graft substitute should reabsorb with time to allow and encourage new bone formation whilst maintaining its properties as an osteoconductive scaffold until it is no longer required. A potential disadvantage of some synthetic substitutes is their long dissolution time. Autologous bone grafting is currently considered as the gold standard to restore bone defects. However, clinical benefit is not guaranteed and there is an associated 8–39% complication rate. This has resulted in the development of alternative (synthetic) bone substitutes. https://biomedpharmajournal.org/vol8octoberspledition/bone-substitues-in-prosthodontic-service/ osteoconductive Bones bone substitutes