eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-10-25 8 October Spl Edition 329 333 10.13005/bpj/699 3494 article C. A. Prakash 1 J. Parthiban 2 R. Balakrishnan 3 B. Anandh 4 B. Lokesh 4 Department of Oral and Maxillofacial Surgery, Tagore Dental College and Hospital, Chennai Department of Oral and Maxillofacial Surgery, Tagore Dental College and Hospital,Chennai,Rathinamangalam, Melakottaiyur Post,Chennai-600127 Department of Oral and Maxillofacial surgery, Sree Balaji Dental College, Bharath University, Pallikaranai, Chennai-600100 Department of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Tagore Dental College and Hospital,Chennai,Rathinamangalam, Melakottaiyur Post,Chennai-600127 Bone Morphogenetic Proteins(BMPs) are a group of growth factors and cytokines known for their ability to induce the formation of bone and cartilage.Originally seven such proteins were discovered.Of these six (BMP2 to BMP7)belong to TGF-B superfamily of proteins.BMP1 is a metalloprotease.Since then thirteen more BMPs have been discovered bringing the total to twenty.MarshallUrist proposed the name’BONEMORPHOGENETIC PROTEIN’ in thescientific literature in ‘Journal of Dental Research’in 1971.BMPs interact with specific receptors on the cell surface referred to as bone morphogenetic protein receptors(BMPRs).BMPs are now produced using recombinant DNA technology.BMP is the most promising osteoinductive protein for bone induction and regeneration. Recombinant human BMP(rhBMP) stimulates osteoblast differentiation in various cells in vitro and induces ectopic bone formation invivo.These formulations have found applications in many disciplines of medicine and dentistry.Orthopaedic  and Oral surgery have benefitted greatly from commercially available BMP formulations in the last few years. https://biomedpharmajournal.org/vol8octoberspledition/bone-morphogenetic-proteins-an-update/ Bone Morphogenetic Proteins  Growthfactors  Osteoinduction  Reconstruction