eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-12-28 8 2 1165 1172 10.13005/bpj/872 6110 article Amir Ahmad Salmasi 1 Abdolhassan Talaeizadeh 2 Mehrnoosh Esmaeili 2 Department of Surgery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. School of Medicine Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Breast cancer is one of the most common cancers in Iranian women. Estrogen and progesterone receptors have been described as a prognostic factor in breast cancer. Axillary lymph node status is also one of the most powerful prognostic factors for patients with breast cancer. The relationship between Estrogen receptor (ER) and progesterone receptor (PR), and axillary lymph node is still controversial. This study aims to investigate the relationship of ER and PR with axillary lymph node among women with breast cancer. Estrogen and progesterone receptors were evaluated by immunohistochemistry assessments in 200 breast cancer patients. Statistical comparison was performed between ER and PR and nodal status. Of the 200 carcinoma tissue samples (mean age. 51.34 years), 133 cases (66.5%) were positive for estrogen receptor, of them 94 cases (70.7%) were positive for axillary nodal involvement. Sixty seven cases (33.5%) were negative for ER, of them 41 cases (61.2%) were positive for axillary nodal involvement. One hundred-eighteen cases (59%) were positive for progesterone receptor, of them 82 cases (69.5%) were positive for axillary nodal involvement. Eighty two cases (41%) were negative for PR, of them 53 cases (64.6%) were positive for axillary nodal involvement. There is no significant relationship between ER and axillary nodal involvement (P=0.397). In addition, there is no significant relationship between PR and axillary lymph node involvement (P: 0.825). There is no relationship between ER and PR status and axillary nodal involvement. https://biomedpharmajournal.org/vol8no2/evaluation-of-the-relation-between-lymph-node-status-and-estrogen-and-progesterone-receptors-status-in-breast-cancer-patients-in-ahvaz-hospitals/ Estrogen receptor Progesterone receptor Breast cancer Axillary lymph node