eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-12-28 8 2 869 874 10.13005/bpj/836 3317 article Seyyed Mohsen Pouryaghobi 1 Mojtaba Ahmadinejad 2 Banafsheh Mashak 1 Mohsen Ebrahimi 3 Ehsan Bolvardi 3 Amir Masoud Hashemian 3 Department of Anesthesiology,Alborz University of Medical Sciences,Karaj,Iran. Department of Surgery, Alborz University of Medical Sciences,Karaj,Iran. Assistant Professor of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Associate Professor of Emergency Medicine, Alborz University of Medical Sciences,Karaj,Iran. Spinal anesthesia is commonly done using lidocaine %5 and bupivacaine %0/5 in various surgeries. This method is accompanied with many complications including spreading anesthetic level to areas higher than that of local injection site. The aim of this study was to determine the spread of sensory block level in spinal anesthesia by using oflidocaine %5 and bupivacaine %0/5 in surgical patients. In a randomized clinical trial, 300 male and female patients who had undergone surgery by spinal anesthesia were randomly divided into two groups (lidocaine %5 and bupivacaine %0/5). After spinal anesthesia, the sensory block levels were checked every 5 minutes by the way of pin prick test and the results were recorded in a checklist. Data were analyzed using SPSS software. The highest anesthetic level in lidocaine %5 and bupivacaine %0/5 groups  was C2 with  %0.7 and C5 with %0.7 of cases respectively (p> 0/05). The mean times of getting to the highest sensory block level in lidocaine %5 and bupivacaine %0/5 groups were 11.53 minutes (+/- 6.24) and 11.87 minutes ( +/- 5.54) respectively after spinal anesthesia (p> 0.05). Anesthetic spreading to C1- C7 and T1- T4 dermatoms in lidocaine %5 group was accomplished in %1.3 and %10 of cases, and it was also reported for the same dermatoms in bupivacaine group %0.7 and %8 of cases respectively (p <0.05). Spinal anesthesia with bupivacaine %0/5 had lower sensory block distribution as compared to lidocaine %5, and it had lower complications compared to lidocaine%5. Therefore, in order to obtain the desirable sensory block level, the use of bupivacaine %0/5 is recommended. https://biomedpharmajournal.org/vol8no2/comparison-of-the-level-of-sensory-blockage-in-spinal-anesthesia-with-bupivacaine-0-5-and-lidocaine-5-in-surgical-patients/ Spinal anesthesia Lidocaine %5 Bupivacaine %0/5 Sensory block level