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<records>

  <record>
    <language>eng</language>
          <publisher>Oriental Scientific Publishing Company</publisher>
        <journalTitle>Biomedical and Pharmacology Journal</journalTitle>
          <issn>0974-6242</issn>
            <publicationDate>2015-12-28</publicationDate>
    
        <volume>8</volume>
        <issue>2</issue>

 
    <startPage>573</startPage>
    <endPage>580</endPage>

	 
      <doi>10.13005/bpj/800</doi>
        <publisherRecordId>4891</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Antiviral and Antidermatophytic Activity of a Compound Extracted from Cuminum Cyminum Seeds</title>

    <authors>
	 


      <author>
       <name>M. M. Mohamadein</name>

 
		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>R. M. Farrag</name>


		
	<affiliationId>2</affiliationId>

      </author>
    

	 


      <author>
       <name>A. A. I. Mekawey</name>

		
	<affiliationId>2</affiliationId>
      </author>
    

	


	


	
    </authors>
    
	    <affiliationsList>
	    
		
		<affiliationName affiliationId="1">The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo-Egypt</affiliationName>
    

		
		<affiliationName affiliationId="2">Collage of Applied Medical Science, Prince Sattam Bin AbdulAziz University, Al-Kharj, KSA</affiliationName>
    
		
		
		
		
	  </affiliationsList>






    <abstract language="eng"><em>In vitro</em> activity of EHP [1-(2-Ethyl, 6-Heptyl) Phenol], a natural compound purified from cumin seeds extract, was investigated against ten dermatophytic isolates;<em> Trichophyton</em> (n=5), <em>Microsporum</em> (n=4), and <em>Epidermophyton </em>(n=1), as well as three viruses; HAV, Cox B4, and HSV-1. The highest antidermatophtic activity was against <em>T. fulvum</em> and <em>E. floccosum</em> while <em>T. terrestre</em> exhibited the most resistant isolate followed by <em>T</em>. <em>schoenleinii</em>. MIC of EHP ranged from 2.5 to 25 µg/ml, however owing to cytotoxicity results, EHP concentrations up to 10 µg/ml are preferably used. EHP possessed antiviral activity against the investigated viruses with HAV being the most affected followed by Cox B4 and then HSV1 with a plaque reduction percentage of 70, 65, and 60, respectively.</abstract>

    <fullTextUrl format="html">https://biomedpharmajournal.org/vol8no2/antiviral-and-antidermatophytic-activity-of-a-compound-extracted-from-cuminum-cyminum-seeds/</fullTextUrl>

<keywords language="eng">

      
        <keyword><em>Cuminum cyminum</em></keyword>
      

      
        <keyword> Viruses</keyword>
      

      
        <keyword> Dermatophytes</keyword>
      

      
        <keyword> EHP</keyword>
      
</keywords>
  </record>
</records>