eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-06-18 8 1 251 254 10.13005/bpj/605 1500 article Sadeghi Limanjoob Reza 1 Tarahomi Mohammad 1 Farzam Mohsen 2 Azhdari Sara 2 Mohammadi Sahar 3 Rostami Ali 1 Department of Aquatic Animal Health, Veterinary School, Kazerun Branch, Islamic Azad University, Kazerun, Iran. Department of Physiology, Veterinary School, Kazerun Branch, Islamic Azad University, Kazerun, Iran. Department of clinical Biochemistry,Kermanshah University of Medical Sciences,Kermanshah,Iran Department of Physiology, Medical School, Kazerun Branch, Islamic Azad University, Kazerun, Iran. damages of the Carp edible muscular tissues are including lesions caused by parasitic, viral, bacterial disease, environmental factors, nutritional effects, poisonings, neo- plastic diseases and also fungal diseases. These lesions in addition to economical losses for the suburbanite of the Parishan Lake, can also threaten the health of human society. So the aim of this study is histopathological investigation of edible muscular tissues of Carp fish of the Parishan Lake, to confirm its health for human society. in this study, 100 pieces of Carp fish (mainly yellow Carp fish) at different weights were caught from Parishan Lake. Fish were initially autopsied. The fixed tissues were dehydrated, became transparent and parafinated and their histological sections were prepared. Those sections were stained by the method of Hematoxylin and Eosin (H & E). Then, they were studied and examined by optical microscope. the results show that in most cases were not observed any specific microscopic lesions, but in some cases the symptoms such as being Melanized, being pale and appearance of Necrotic tumors in muscular tissues were observed in the muscle tissues.  No tissues’ damage was observed in 60% of the cases, but in the remaining the following signs were observed, 8% Hyperemia, 22% inflammatory cells and in 10% Necrosis. according to the survey, it was found that histopathological lesions were created due to the unfavorable environmental conditions such as water reduction of the lake, loss of some aquatic of the lake and disrupting in its natural cycle and arrival of waste water and residual water of surrounding villages into the lake. Therefore it is recommended to do necessary proceedings to reduce the histopathological waste. https://biomedpharmajournal.org/vol8no1/histopathological-investigation-of-edible-muscular-tissues-of-carp-fish-related-to-parishan-lake-in-order-to-confirm-thier-safety-in-humans/ histopathologic edible muscles Carp fish Parishan