eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-05-02 7 1 17 22 10.13005/bpj/447 2824 article Amin Mohammadi 1 Ali khajehlandi 1 Department of Physical Education and Sport Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran. Obesity is a condition of excess body fat. It has been known as major public health problem, was reported to be associated with insulin resistance, type 2 diabetes mellitus and cardiovascular disorders. Therefore the purpose of this study was to examine the effects of aerobic training on hs-CRP and adipokin (as Lcn2) in obese young men. Thirty healthy young men (aged 27.83 ± 1.69years, height 1.71± 5.37 cm, BMI 30.1 ± 1.49 kg/m2, mean ± SD) participated as subjects in this study. The subjects were randomly assigned to aerobic training group (n=15) or control group (n= 15). Aerobic training group underwent an 8-week intervention, with a frequency of 3 d/wk at an intensity corresponding to 65 – 80% maximum heart rate for 35 – 55 min. The results showed that body fat percent, WHR, BMI, were decreased ((P<0.05), in the training group compared with control group. Maximum oxygen consumption, on the other hand, increases significant (P<0.05) in the training group compared with the control group. Adipokin lcn-2, LDL-c, TG, TC decreased (P<0.05) and HDL-c increased (P<0.05). No significant changes in hs-CRP were found after 8 weeks aerobic training. It seems that 8 weeks aerobic training induced change in adipose tissue, decrease Adipokin (Lcn2), but this improvement was not accompanied by decreased hs-CRP in young obese men. https://biomedpharmajournal.org/vol7no1/hs-crp-and-adipokin-lcn2-response-to-exercise-training-in-obese-men/ Aerobic training Adipokin hs-CRP obese men