eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-04-27 6 1 111 124 2640 article Sibi Jose 1 S.A. Iqbal 2 Department of Chemistry, Sadhu Vaswani College, Bairagarh, Bhopal - 462 001, India. Department of Chemistry, Crescent College of Technology, Bhopal - 462 038, India. This paper deals with the synthesis and characterization of a glimepiride-neodymium complex, rare earth’s metal. Glimepiride is an oral hypoglycemic agent. The conductometric titrations were conducted using monovariation method which shows the ligand metal ratio as 2:1. Molar conductance value indicate that complex is non-ionic in nature. Analytical results agree to the molecular formula (C24H34N4O5S)2 Nd.4H2O. rare earth’s element Nd shows the high coordination sites. The structure of the complex was assigned as hexagonal in which ligand moleculas joining the central Nd(III) atom with nH2O molecules. Infrared spectral studies have supported coordination of sulphonyl oxygen on one side and enolic oxygen attached from other side and four water molecule attached by four co-ordination sides with the neodymium ion. Mass spectral, thermal and magnetic studies supports structure of the complex proposed on the basis of analytical data X-ray diffraction studies. https://biomedpharmajournal.org/vol6no1/synthesis-characterization-and-antidiabetic-study-of-nd-iii-complex-of-1-p-2-3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamidoethyl-phenylsulfonyl-3-trans-4-methyl-cyclohexyl-urea-amaryl-or/ Synthesis Characterization neodymium-Glimepiride complex