eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-03-29 4 2 245 248 1939 article Hossein Hosseinzadeh 1 Department of Chemistry, Payame Noor University, 19395-4697, Tehran (Iran). Novel biopolymer-based superabsorbent hydrogels were prepared by grafting crosslinked poly(acrylic acid-co-methacrylic acid) chains onto gelatin backbones through a free radical polymerization method. The graft copolymerization reaction was carried out in a homogeneous medium and in the presence of ammonium persulfate (APS) as an initiator and N,N’-methylene bisacrylamide (MBA) as a crosslinker. Under optimized reaction conditions, hydrogel has an absorbency of 340 g/g for distilled water. Swelling ratio in various salt solutions was also determined and additionally, the swelling of hydrogels was measured in solutions with pH ranged from 1 to 11. https://biomedpharmajournal.org/vol4no2/optimization-of-environmental-chemical-factors-affecting-on-swelling-capacity-of-a-novel-protein-based-hydrogel/ Gelatin Hydrogel Acrylic acid Methacrylic acid Swelling behavior