eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-03-29 4 2 291 295 2006 article Malathi Jojula 1 V. Kondal Rao 2 Jyotsna Vihnudas 3 Department of Pharm. Microbiology, Sri Shivani College of Pharmacy, Warangal India. Department of Microbiology, Kakatiya Medical College, Warangal India. Department of Pharm. Biochemistry, Sri Shivani College of Pharmacy, Warangal India. Diagnosis of sputum/smear-negative pulmonary tuberculosis patients can be both challenging and time consuming with many patients being put on empirical anti-tubercular treatment. The study was conducted on100 suspected sputum smear negative pulmonary tuberculosis causes attending ICTC of MGM District Hospital Warangal. All the suspect’s sputum was screened for AFB staining were shown negative. Their mode of clinical presentation, site of TB, CD4 cell count, dysentery in HIV, TB, studied. Tuberculosis (TB) was found in 15% of HIV infected patients those were showing smear negative for AFB. TB were significantly more common in HIV seropositive patients (p< 0.02) in whom the CD4 cell count was also low (less than 100/cmm).8% of dysentery was found among them. The result of this study showed the increased vulnerability of the HIV infected persons to TB infection as seen in other studies in India and abroad. Disseminated TB with lower CD4 cell count is also shown. Smear negative persons were more prone for tuberculosis infection which may become problem in diagnosis and treatment of tuberculosis. https://biomedpharmajournal.org/vol4no2/diagnosing-sputumsmear-negative-pulmonary-tuberculosis-in-plhiv-based-on-culture-a-study-from-mgm-district-hospital/ HIV/AIDS Smear negative TB CD4 Counts diherial