eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-03-28 4 1 231 235 1916 article Rina Sharma 1 Rehana Najam 1 Manish Kumar Misra 2 Department of Obstetrics and Gynecology, Teerthankar Mahaveer Medical College, Moradabad (India). Department of Biochemistry, Teerthankar Mahaveer Medical College, Moradabad (India). The aim of present investigation is to study the efficacy and safety of tranexamic acid in reducing blood loss during and after cesarean section. Tranexamic acid is a competitive inhibitor of plasminogen activation, and at much higher concentrations, a noncompetitive inhibitor of Plasmin. Plasmin may be formed by conformational changes in plasminogen, it’s binding to and dissolution of the fibrin matrix is inhibited. Tranexamic acid significantly reduces the amount of blood loss during and after the lower segment cesarean section. The use of tranexamic acid was not associated with any side effects or complication like thrombosis, nausea, vomiting and diarrhea. https://biomedpharmajournal.org/vol4no1/efficacy-of-tranexamic-acid-in-decreasing-blood-loss-during-and-after-cesarean-section/ Tranexamic acid Side effects Blood loss Cesarean Section