eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-03-25 3 1 183 186 1365 article Pharmacological Study of the Glibenclamide and Glimeperide Mixed Ligands and their Zinc Complexes Mohammad Tawkir 1 S. A. Iqbal 2 S. B. Kapoor 2 Department of Chemistry, Arts Commerce and Science College Tukum, Chandrapur India. Department of Chemistry, Saifia College of Science and Education, Bhopal - 462 001 India.

Present Communication deals with the preliminary study fo the comparison of hypoglycemic activity of two mixed sulphonyl urea. i.e. Glibenclamide (5-chloro-N-(4- N-cyclohexyl carbonyl) sulfamoyl] phenethy] 2-methoxybenzamide (L1) adn Glimeperide (3-ethyl-4-methyl-N-(4-[N-(1r,4r)-4-methylcyclohexl carbamoyl) sulfamoyl] phenethyl)-2-oxo-2, 5-dihydro-1-H-pyrrole-1-Carboxamide (L2) in equal proportion with zinc - complex of these mixed drugs result reveals that the ternary (L1ML2) complex of these drugs with zinc gives surprising results.

 https://biomedpharmajournal.org/vol3no1/pharmacological-study-of-the-glibenclamide-and-glimeperide-mixed-ligands-and-their-zinc-complexes/

Pharmacological study Mixed ligands metal complexes