The antibacteria properties of Indian medicinal plant extracts of syzygium alternifolium, phyllanthus niruri and rubia cord folia against six bacteria strains (Escherichia coli, bacillus subtilis, Staphylococcus aureus, Klebsiella Pneumonia, Pseudomonas aeruginosa and proteus vulgaris have been studies, Chloroform, ethanol and aqueous extracts were prepared sequentially from leaves fo Syzygium, phyllanthus and Rubia plants, it was observed that methanol and ethanolic extracts fo Synygium have significant activity against gram positive bacteria. Klebsiella pneumonia and proteus vulgaris were more sensitive to the extracts of phyllanthus niruri and Rubia cordifolia respectively.