An Efficient Synthesis, Characterization of some Novel 6 -(R) phenyl-azo-coumarin -3- carboxy(3-chloro- 4-methoxy) anilide and 2- hydroxy- 5(R)-phenyl – azo – benzylidine (3- chloro – 4 -methoxy)aniline and their Antibacterial Activity

eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-03-25 3 1 141 146 1254 article An Efficient Synthesis, Characterization of some Novel 6 -(R) phenyl-azo-coumarin -3- carboxy(3-chloro- 4-methoxy) anilide and 2- hydroxy- 5(R)-phenyl – azo – benzylidine (3- chloro – 4 -methoxy)aniline and their Antibacterial Activity Alok K. Pareek 1 P. E. Joseph 1 Daya S. Seth 1 School of Chemical Sciences, Department of Chemistry, ST. John’s College, Agra - 282 002 India.

An efficient synthesis of various substituted azo-coumarin & azo-Schiff base has been synthesized by the condensation of 3-chloro-4-methoxy phenyl malon anilic acid (1a) and different substituted phenyl benzene-azo-salicylaldehyde (5a-5l) with few drops of pyridine as a condensing agent. The constitution of the newly synthesized products has been established on the basis of their spectral studies viz: IR, 1H NMR, Elemental analysis and physical properties as m.p, colour, yield%, molecular formula etc. and their antibacterial activity was carried out against S.aureus and E.coli micro-organisum.

https://biomedpharmajournal.org/vol3no1/an-efficient-synthesis-characterization-of-some-novel-6-r-phenyl-azo-coumarin-3-carboxy3-chloro-4-methoxy-anilide-and-2-hydroxy-5r-phenyl-azo-benzylidine-3-chloro-4-methoxyanili/

Subs. Azo - Coumarins Azo - Schiff’s Bases Pyridine Condensation Malonic Acid