eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-02-16 2 2 339 343 825 article Omair Hasan Osmani 1 Dhanasekar Sathish Sekar 1 K.L. Senthil Kumar 1 Ram Kumar Sahu 2 Amit Roy 3 Department of Pharmacognosy, Padmavathi College of Pharmacy, Dharmapuri (India). Department of Pharmacognosy, Oriental College of Pharmacy, Bhopal (India). Columbia College of Pharmacy, Mandhar, Raipur (India). Artocarpus heterophyllus is a medicinal plant, used by herbalist for treating various diseases, one of which is Diabetes mellitus. The aim of this study was to investigate the antidiabetic potential of Artocarpus heterophyllus plant seed powder. This was tested in normal and strepozotocin induced diabetic rats using oral administration of ethanol extracts of Artocarpus heterophyllus. After the oral administration of ethanol extract at doses of 400 mg/kg body weight, blood glucose levels were monitored at specific intervals and found significantly lowered the blood glucose level. Glibenclamide was used as a standard drug at a dose of 0.25 mg/kg. The experimental data revealed that extract has significant antihyperglycaemic activity in streptozotocin-induced rats compared to standard drug. The extracts seem promising for the development of an oral antidiabetic medicine. https://biomedpharmajournal.org/vol2no2/in-vivo-antidiabetic-potential-of-artocarpus-heterophyllus-plant-seeds-in-streptozotocin-induced-diabetic-rats/ Antidiabetic Lipid profile Artocarpus heterophyllus Strepozotocin Glibenclamide