eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-02-16 2 2 287 292 804 article Lakhdar Sekhri 1 Nedjimi 1 Department of Chemistry, University of Ouargla - 300 00 (Algeria). A range of prochiral acetophenone derivatives have been converted efficiently to the corresponding (R)- alcohols with > 80% yield and good enantioselectivities (up to 70% ee). Cyclic ketones are also reduced with high levels of stereoselectivity with PMHS in the presence of TBAF and baker’s yeast, in particular 4-methylcyclohaxanone (trans: cis 84:16). High stereoselectivity is also observed in the reduction of 2-cyanobenzaldehyde and anti-imine was obtained in 71%. https://biomedpharmajournal.org/vol2no2/a-convenient-procedure-for-the-asymmetric-reduction-of-prochiral-ketones-using-tetrabutylammoniumffluoride-polymethylhydrosiloxane-and-biocatalysts-bakers-yeast/ Asymmetric reduction biocatalyst backer’s yeast TBAF PMHS