A Simple, Rapid, Precise and Accurate Spectrophotometric Method has Been Developed for Estimation of Lercanidipine from Tablet Formulation. In Ethanol, Lercanidipine Showed Absorbance at 239 Nm. Linearity was Observed In the Concentration Range Of 2-28 µg/Ml. The Assay Result was Found to be in Good Agreement with Label Claim. The Recovery Studies were Carried out at Three Different Levels. The Method was Validated Statistically and by Recovery Studies.

G. Mubeen; Damanjit Singh Rao; Kadri Uvesh

Mubeen G, Rao D. S, Uvesha K. Simple, Rapid, Precise and Accurate Spectrophotometric Method has Been Developed for Estimation of Lercanidipine from Tablet Formulation. In Ethanol, Lercanidipine Showed Absorbance at 239 Nm. Linearity was Observed In the Concentration Range Of 2-28 µg/Ml. The Assay Result was Found to be in Good Agreement with Label Claim. The Recovery Studies were Carried out at Three Different Levels. The Method was Validated Statistically and by Recovery Studies.Biomed. Pharmacol. J.;1(2)

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Published online on: 09-11-2015

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A Simple, Rapid, Precise and Accurate Spectrophotometric Method has Been Developed for Estimation of Lercanidipine from Tablet Formulation. In Ethanol, Lercanidipine Showed Absorbance at 239 Nm. Linearity was Observed In the Concentration Range Of 2-28 µg/Ml. The Assay Result was Found to be in Good Agreement with Label Claim. The Recovery Studies were Carried out at Three Different Levels. The Method was Validated Statistically and by Recovery Studies.

G. Mubeen*, Damanjit Singh Rao and Kadri Uvesh

Department of Quality Assurance, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Bangalore - 560 027 (India).

Abstract

A simple, rapid, precise and accurate spectrophotometric method has been developed for estimation of Lercanidipine from tablet formulation. In ethanol, Lercanidipine showed absorbance at 239 nm. Linearity was observed in the concentration range of 2-28 µg/mL. The assay result was found to be in good agreement with label claim. The recovery studies were carried out at three different levels. The method was validated statistically and by recovery studies.

Keywords

Lercanidipine; spectrophotometry; validation

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Mubeen G, Rao D. S, Uvesha K. Simple, Rapid, Precise and Accurate Spectrophotometric Method has Been Developed for Estimation of Lercanidipine from Tablet Formulation. In Ethanol, Lercanidipine Showed Absorbance at 239 Nm. Linearity was Observed In the Concentration Range Of 2-28 µg/Ml. The Assay Result was Found to be in Good Agreement with Label Claim. The Recovery Studies were Carried out at Three Different Levels. The Method was Validated Statistically and by Recovery Studies.Biomed. Pharmacol. J.;1(2)

(Visited 94 times, 1 visits today)