eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 47 50 201 article E.k. NWANGWA 1 C.r. NWOKOCHA 1 U.e. UZUEGBU 1 S.I. OVUAKPORAYE 1 Department of Physiology and *Department of Medical Biochemistry College of Health Sciences, Delta State University Abraka (Nigeria). The bioconcentration of mercury in the kidney and liver of rats was studied. Twenty-four wister rats were randomly divided into four experimental groups(n=6). GroupA(control)were given rat chow and drinking water .Group B (given rat chow +10% by mass of Solanum lycopersicum(sl). Group C ( given rat chow + mercury in water at a concentration of 10ppm . Group D (given rat chow +Hg in 10ppm+10% by mass of sl). The result shows a statistically significant increase (P<0.05) in the concentration of mercury in the liver and kidney. There was also a statistically significant increase (P<0.05) in liver enzyme- Glutamate Pyruvate Transaminase(GPT) and Glutamate oxaloacetate Transaminase (GOT), which shows the destructive effects of mercury in the organs. The study also shows a statistically significant decrease in the destructive effects as a result of the administration of Solanium lycopersicum. https://biomedpharmajournal.org/vol1no1/the-bioaccumulation-of-mercury-in-kidney-and-liver-of-wistar-rat-exposed-to-methyl-mercury/ Bioaccumulation Mercury poisoning Solanum lycopersicum Liver enzymes