eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 195 200 306 article Ambuj Singh 1 S. K. Prajapati 2 K. P. Namdeo 2 V. K. Singh 2 S. K. Verma 2 Institute of Pharmacy, Bundelkhand University, Jhansi S. L. T. Institute of Pharmaceutical Sciences, G.G.U., Bilaspur, Chhatisgarh Synthesis of six 2,3,6-trisubstituted Quinazolin-4-one is reported. All six compounds contain a bromine atom at position 6, phenylimino thiazolidinone group at position 2 and 3 different derivatives has been synthesized by changing X (A-1: benzaldehyde, A-2: m-chlorobenzaldehyde, A-3: o-hydroxybenzaldehyde, A-4: p-methoxybenzaldehyde, A-5: o-nitrobenzaldehyde, A-6: m-nitrobenzaldehyde). All the synthesized compounds work evaluated for their antimicrobial (against two gram positive and two gram negative microorganism) and antifungal activity (against A. niger and C. albicans). https://biomedpharmajournal.org/vol1no1/synthesis-and-antimicrobial-activity-of-some-quinazolinone-derivatives/ Antimicrobial activity Quinazolinone derivatives