eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 213 218 334 article S. K. Verma 1 R. Irrchhaiya 2 K. P. Namdeo 2 K. P. Namdeo 2 A. Singh 2 S. Khurana 3 Institute of Pharmacy, Bundelkhand University, Jhansi. S.L.T Institute of Pharmaceutical Sciences G.G.U., Bilaspur. I.T.S. Paramedical college, Ghaziabad. Some new 6-phenyl–Pyridazine-3-One were synthesized by hydrazinolysis of appropriate b-(substituted aryl) propionic acid, there were converted into corresponding Bis-pyridazinone (IIIa toIIId). All these synthesized compounds were characterized on the bases of spectral data and evaluated for their antimicrobial activity. https://biomedpharmajournal.org/vol1no1/synthesis-and-antimicrobial-activity-of-some-pyridazinone-derivatives/ Pyridazine-3-One Antibacterial activity Antifungal activity