eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 173 176 294 article Ravindra Kumar 1 Birbal Bajia 1 Y. K. Srivastava 1 P.G. Department of Chemistry, M. P. Government College Chittorgarh. Pyrazoline derivatives have their importance due to a variety of industrial applications and wide range of biological activities change in substitution pattern at 1-N position of pyrazoline ring may alter the biological activities of pyrazolines. Therefore some new 1-N substituted pyrazoline derivatives were synthesized using microwave assisted method. The condensation of chalcone with hydrazine gave 3, 5-diaryl-2 pyrazolines which were treated with chloro acetyl chloride followed by reaction with diethyl amine to afford corresponding 1-N substituted 3, 5-diaryl pyrazolines in 80-85% yield. The synthesized compounds were screened for their anti bacterial activities against gram negative and gram positive bacteria. https://biomedpharmajournal.org/vol1no1/synthesis-and-antibacterial-activity-of-some-pyrazolines-using-more-technique/ Pyrazoline microwave assisted anti bacterial activity