eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 89 100 230 article S. Girija 1 V. Y . Rajalakhsmi 1 Department of Plant Biology and Biotechnology, Ethiraj college for women, Chennai. Momordica charantia Linn. belongs to the family cucurbitaceae. It is a medicinal plant used for many diseases. It is a climbing annual or perennial herb is used as vegetable. I have studied its phytotoxic effect in both in vitro and in vivo analyses. It was studied by using the ethanolic extract of leaf and fruit of Momordica charantia on common weeds like Commelina and Aerva by leaf disc assay. Leaf discs of Commelina and Aerva were incubated for 24 and 48 hrs in the ethanolic extract. The result shown remarkable reduction in the chlorophyll content. These result suggest that the fruit and leaf extract of Momordica charantia possesses the phytotoxic effect. https://biomedpharmajournal.org/vol1no1/phytotoxic-effect-of-momordica-charantia-on-common-weeds-commelina-aerva/ Phytotoxicity Ethanolic extract phytochemical analysis secondary metabolites