eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 127 130 259 article R. Radha 1 S. Arokiyaraj 2 P. Agastian 2 K. Balaraju 2 R. Mohan Kumar 3 P. Bula 4 Department of Pharmaceutical Sciences, Madras Medical College, Chennai . Department of Biotechnology, Loyola College, Chennai . Astagiri Herbal Research Foundation, Chennai . Rovers College of Arts and Science, Tamil Nadu . Alcohol and aqueous extract of Pisonia grandis (leaf) was taken and analyzed for anti-inflammatory activity. Preliminary phytochemical screening was performed for both the extracts. In the present study alcohol extract showed significant anti-inflammatory activity in carrageenan induced paw edema rats. Phytochemical analysis of alcohol extract revealed the presence of flavanoids, steroids, furan, alkaloids, anthraquinone, tannins and saponins but negative result was observed in aqueous extract except tannins. This study showed vital information regarding pharmacological and phytochemical activities of P. grandis. https://biomedpharmajournal.org/vol1no1/phytochemical-analysis-and-anti-inflammatory-activity-of-pisonia-grandis-r-br/ Acute toxicity anti-inflammatory  diclofenac sodium Pisonia grandis