<?xml version="1.0" encoding="UTF-8"?>



<records>

  <record>
    <language>eng</language>
          <publisher>Oriental Scientific Publishing Company</publisher>
        <journalTitle>Biomedical and Pharmacology Journal</journalTitle>
          <issn>0974-6242</issn>
            <publicationDate>2015-01-20</publicationDate>
    
        <volume>1</volume>
        <issue>1</issue>

 
    <startPage>101</startPage>
    <endPage>106</endPage>

	    <publisherRecordId>238</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Comparative Evaluation of Releasing Rate of Nifedipine in S.R. Products from Indian Market by Spectrophotometry</title>

    <authors>
	 


      <author>
       <name>Bincy Thomas</name>

 
		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>V. V. Pande</name>


		
	<affiliationId>2</affiliationId>

      </author>
    

	 


      <author>
       <name>A. R.Tekade</name>

		
	<affiliationId>3</affiliationId>
      </author>
    

	 


      <author>
       <name>K. V. Shastri</name>

		
	<affiliationId>4</affiliationId>
      </author>
    


	


	
    </authors>
    
	    <affiliationsList>
	    
		
		<affiliationName affiliationId="1">Departemnt of Pharmaceutical Analysis, Allana College of Pharmacy, Pune.  4Department of Pharmaceutics, R.C. Patel College of Pharmacy, Shirpur.</affiliationName>
    

		
		<affiliationName affiliationId="2">Department of Pharmaceutical Analysis, Jayawantrao Sawant College of Pharmacy and Research, Hadapsar, Pune.   </affiliationName>
    
		
		<affiliationName affiliationId="3">Departement of Pharmacognosy and Phytochemistry Vivekanand Education Society’s College of Pharmacy Chembur (E), Mumbai.  </affiliationName>
    
		
		<affiliationName affiliationId="4">Department of Pharmaceutics, R.C. Patel College of Pharmacy, Shirpur.</affiliationName>
    
		
		
	  </affiliationsList>






    <abstract language="eng">Nifedipine, a calcium channel blocker inhibits the movement of calcium ions across the membranes of cardiac and arterial muscle cells is mainly indicated in angina pectoris, hypertension, raynaud’s phenomenon, myocardial infarction and asthma. It is recommended to administer Nifidipine as modified release dosage form in order to avoid fluctuations in blood vessels. There are several brands of Nifedipine available in the Indian market. Two of such brands of Nifedipine BRAND A and BRAND B were procured from the Indian market and were subjected to spectrophotometric analysis by comparing with the control in order to determine their dissolution patterns. The results indicated that not all the brands of Nifedipine exhibit the same therapeutic effect as there was variation in the release of the active ingredient at the various time intervals and at different levels of pH.</abstract>

    <fullTextUrl format="html">https://biomedpharmajournal.org/vol1no1/comparative-evaluation-of-releasing-rate-of-nifedipine-in-s-r-products-from-indian-market-by-spectrophotometry/</fullTextUrl>

<keywords language="eng">

      
        <keyword><b> </b>Nifedipine sustained release</keyword>
      

      
        <keyword> spectrophotometery</keyword>
      

      
        <keyword> absorbance</keyword>
      
</keywords>
  </record>
</records>