eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2015-01-20 1 1 85 88 218 article N. Rahimifard 1,2 Sh. Shoeibi 1,2 S. R. Pakzad 1,2 H. Hajimehdipoor 1,2 O. Sabzevari 3 S. Ajdary 4 Food and Drug Laboratory Research center (FDLRC), Tehran (Iran) Food and Drug Control Laboratories (FDCLs), Ministry of Health (MOH), Tehran (Iran) Pharmacy faculty, Tehran University of Medical Sciences(TUMS), Tehran (Iran) Immunology Department, Pasteur Institute, Tehran (Iran) Microbiology Department, Pharmaceutical sciences branch, Islamic Azad University, Tehran (Iran) The composition of the essential oil of Cinamomum zeynalicum and its antifungal activity on Candida albicans, Aspergillus niger and Aspergillus flavus fungal strains were studied in Iran. Essential oil from the bark parts of the plant was obtained by hydrodistillation and analysed by GC and GC-MS. The MIC was used to evaluate the antifungal activity against Candida albicans ATCC 10231, Aspergillus niger ATCC 9642 and Aspergillus flavus ATCC 9643. Antifungal activity was evaluated for the essential oil and simultaneously for Amphotricin B. Results showed that Cinamomum zeynalicum essential oil exhibited a significant activity against fungi, and its MIC on Candida albicans, Aspergillus niger and Aspergillus flavus were respectively 0.125, 0.125 and 0.125 µg ml-1 (ppm).The present study indicates that Cinamomum zeynalicum essential oil has considerable antifungal activity, deserving further investigation for clinical applications. https://biomedpharmajournal.org/vol1no1/antifungal-activity-of-the-essential-oil-of-cinamomum-zeynalicum-on-candida-albicans-aspergillus-niger-and-aspergillus-flavus/ Cinamomum zeynalicum  MIC(minimal inhibitory concentration) Antifungal activity