eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2026-07-22 19 3 72779 article Vineela Sekharamantri 1 Satyalakshmi Siragam 1 Srinivasa Rao Yarraguntla 1 Lalitha Srilekha Ramanujam 1 Bhavya Reddi 2 Department of Pharmaceutics, Vignan Institute of Pharmaceutical Technology, Duvvada, Visakhapatnam, India. Regulatory Affairs, College of Professional Studies, North-eastern University, Boston, United States. The current research was designed to evaluate the inflammation suppressing and wound healing properties of Albizia lebbeck bark extracts in aqueous and methanolic forms. The study entailed phytochemical analysis of the bark extract, assessment of the suppression of inflammation of aqueous and methanolic extracts via the egg albumin denaturation assay, and then assessment of wound healing activity by Wistar Albino rats through the formulated and evaluated ointments and emulgels. The aqueous extract exhibited the greatest inhibition of denaturation of egg albumin at 68.22 ±0.22 % compared to the methanolic extract. The estimated characteristic properties were fallen within the optimal range for both ointment and emulgel formulations. Six formulations including a control and a standard povidone iodine ointment were tested in triplicate for wound healing activity on Wistar Albino rats over a period of 14 days. The F4 has rapid wound healing capabilities, achieved 99 % wound closure in comparison to other formulations and demonstrated comparable efficacy to povidone-iodine ointment (F6). The overall findings indicated that A. lebbeck bark has potential for use in future ethno medicinal applications as an anti-inflammatory and wound healer, primarily due to its abundance of bioactive molecules. https://biomedpharmajournal.org/vol19no3/wound-healing-activity-of-albizia-lebbeck-bark-extract-in-ointment-and-emulgel-formulation-a-comparative-study/ Albizia lebbeck Anti-inflammatory activity Emulgel Ointment Skin infections Wound healing activity