eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2026-07-17 19 3 72749 article Sunila Bukanakere Sangappa 1 Tatikonda Supriya 1 Christy Thomas 2 Department of Prosthodontics, JSS Dental College and Hospital JSS AHER, Mysuru, Karnataka India Department of Pharmacy Practice National Institute of Pharmaceutical Education and Research, Guwahati, Assam, India Nanotechnology has introduced innovative approaches in dentistry through the integration of biosynthesized nanoparticles into prosthodontic materials, where these nanoparticles, derived from biological sources such as plants, bacteria, fungi, and algae, provide sustainable and biocompatible alternatives to chemically synthesized ones. This scoping review aimed to map the existing evidence on their application in removable and implant prosthodontics, using a systematic literature search of articles published between 2010 and 2025 in PubMed, Scopus, and Google Scholar, following PRISMA-ScR guidelines, including only original research articles and performing both qualitative and quantitative syntheses while analysing studies based on nanoparticle type, synthesis method, prosthodontic application, and biological outcomes. A total of 44 relevant articles were included, of which 57.1% (n = 25) were experimental studies and 38.8% (n = 17) were review articles, with applications spanning denture bases, liners, adhesives, and implant surface coatings. All included studies were in vitro (100%, n = 44), providing short-term biological evaluations, and reported antibacterial activity in 75.0% (n = 33) of studies, antifungal effects in 34.0% (n = 15), biofilm inhibition or surface modification in 27.2% (n = 12), biocompatibility in 20.4% (n = 9), and cytotoxicity assessment in 6.8% (n = 3). Overall, biosynthesized nanoparticles show promising potential in enhancing the biological properties of dental prostheses; however, standardized synthesis protocols along with well-designed in vivo and clinical studies are necessary to establish long-term safety and clinical efficacy. https://biomedpharmajournal.org/vol19no3/influence-of-biosynthesized-nanoparticles-on-the-biological-properties-of-dental-prosthesis-scoping-review/ Biocompatibility Biosynthesized Cytotoxicity Nanoparticles Prosthodontics