eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2026-07-15 19 3 72703 article Augustine Kakou 1 Leffry Habib Ahikpa 1 Yves Cédrick Kee Mankoh 2 Alain Yao N’Guessan 4 Sita Kangah N’Zoué 2 Camille Koffi 2 Laboratory of Clinical Pharmacology, Faculty of Medical Sciences, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire. Department of Clinical Pharmacology and Toxicology, Faculty of Medical Sciences, Alassane Ouattara University, Bouake, Côte d’Ivoire. Department of Ophthalmology, University Teaching Hospital of Cocody, Abidjan, Côte d’Ivoire. Department of Biochemistry-Genetics, Faculty of Biological Sciences, Peleforo Gon Coulibaly University, Korhogo, Côte d’Ivoire. Allergic conjunctivitis is common in young people living in urban areas and is often associated with atopy. This study aimed to evaluate the effectiveness and safety of antihistamine eye drops, as well as their impact on quality of life. This prospective descriptive study was conducted over six months with seventy-seven patients suffering from allergic conjunctivitis at the Department of Ophthalmology at the University Teaching Hospital of Cocody in Abidjan. Data collected included sociodemographic characteristics, allergy history, clinical data, prescribed treatments, symptom progression, patient satisfaction and adverse effects. We then compared our results with data from the literature. A total of 77 patients were included in the study. The majority were female (64.9%), with an average age of 20.4 years, and were pupils or students. Personal (71.4%) and family (19.5%) histories of allergies were present. Olopatadine eye drops were prescribed to 62.3% of patients, at a dosage of one drop twice daily (88.3%). We observed rapid improvement (in less than 15 minutes) in 70% of patients, and satisfaction reached 90.9% when eye washing was performed beforehand. Our research team reported no adverse effects or relapses during follow-up. Antihistamine eye drops, particularly olopatadine, are highly effective and well tolerated, especially when used alongside eye washing. Appropriate management and patient education are necessary to improve the quality of life of patients with atopic conditions. Longer-term studies will enable the durability of the results to be evaluated. https://biomedpharmajournal.org/vol19no3/clinical-outcomes-of-allergic-conjunctivitis-treated-with-antihistamine-eye-drops-and-eye-washing-in-abidjan/ Abidjan Allergic conjunctivitis Antihistamines Atopic Cocody Efficacy Olopatadine eye drops Safety Tolerance