eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2026-09-30 19 3 2153 2175 10.13005/bpj/3484 73117 article Ritu 1 Manish Kumar 1 Sumeet Gupta 1 Manisha Bhatia 1 Department of Pharmacology, Maharishi Markandeshwar College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India Parkinson’s disease (PD) is a chronic neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons, leading to motor and non-motor dysfunctions. Herbal medicinal plants have gained considerable attention because of their potential neuroprotective effects in management of Parkinson disease, which is the need of the hour. This review summarizes the therapeutic potential of vital medicinal plants along with their major bioactive constituents responsible for anti-parkinson effect. Mucuna pruriens contains levodopa, a dopamine precursor effective in improving motor symptoms, while Ginkgo biloba exhibits antioxidant and anti-inflammatory activities that may provide neuroprotection. Bacopa monnieri and Centella asiatica possess neurotrophic, antioxidant, anti-inflammatory, and anti-apoptotic properties that may support dopaminergic neuronal function. Bioactive compounds found in plants such as alkaloids, flavonoids, and polyphenols modulate multiple pathways associated with PD pathogenesis, including oxidative stress, neuroinflammation, mitochondrial dysfunction, and apoptosis. Thus, it is ascertained that a variety of herbal plants and their potent bioactive components have immense potential to be used as adjunctive or substitute therapy for this chronic illness. Although preclinical studies demonstrate promising therapeutic potential, further experimental and clinical validation are of utmost importance to establish the safety, efficacy, and clinical applicability of herbal therapies in Parkinson’s disease management. https://biomedpharmajournal.org/vol19no3/a-comprehensive-and-compendious-review-on-herbal-plants-in-parkinsons-disease-therapy/ Herbal supplements Herbal remedies Medicinal plants Plant-based treatment Parkinson's disease Traditional medicine