eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2026-06-02 19 2 72036 article Siti Maemun 1 Aninda Dinar Widiantari 1 Nourmalita Sari Putri 3 Nina Mariana 1 Rivaldiansyah 1 Maria Lawrensia Tampubolon 1 Clinical Research Unit, Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia Faculty of Health Sciences, Universitas Respati Indonesia, Jakarta, Indonesia Indonesian College of Epidemiology, Indonesian Health Council, Jakarta, Indonesia Medical Record Unit, Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia Research Unit, National Research and Innovation Agency, Jakarta, Indonesia Faculty of Public Health, Universitas Esa Unggul, Jakarta, Indonesia. To develop an appropriate health program, it is essential to understand the specific causes of death, especially those reported on death certificates from health facilities. This cross-sectional study aimed to analyse the sociodemographic data associated with in-hospital deaths in Sulianti Saroso Infectious Disease Hospital (SSIDH), a national infectious disease center in Indonesia. Which analyzed 1,567 Medical Certifications of Cause of Death (MCCD) forms collected from January 2018 to December 2022 at Sulianti Saroso Infectious Disease Hospital. The International Classification of Diseases, 10^th revision (ICD-10) was used to report causes of death. The data analysis of patient mortality revealed trends in minimum and maximum values, as well as median and frequency distribution patterns. Deaths in males predominated (63.1%). The median age was 53 years and the median Length of Stay (LOS) was five days. Most deaths occurred in adults and within ten days of hospitalization. Respiratory diseases were the leading cause, while infectious and parasitic diseases were the main underlying cause in males. There was a significant difference between age groups and the distribution of causes of death based on ICD-10 chapters (p < 0.001). Conversely, gender showed no significant difference in the distribution of either underlying or immediate causes of death (p = 0.161 and p = 0.342). Meanwhile, LOS had a significant correlation with the distribution of both underlying and immediate causes of death (p < 0.001). Male mortality rates were over twice those of females, with the highest deaths occurring in the elderly. Respiratory disorders were the major cause of mortality, particularly in patients with a stay of more than 48 hours.The use of MCCD and hospital medical records may result in misclassification of causes of death. As the study was conducted in a single infectious disease referral hospital during the COVID-19 pandemic, the findings may not represent the general population. Additionally, the descriptive design cannot establish causal relationships. https://biomedpharmajournal.org/vol19no2/a-five-year-epidemiological-study-on-the-profile-of-in-hospital-deaths-in-sulianti-saroso-infectious-disease-hospital/ Cause of Death Diseases Hospital Length of Stay (LoS) Medical Certifications of Cause of Death (MCCD)