eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-12-30 18 4 2715 2725 10.13005/bpj/3288 69487 article Mariia Shanaida 1 Bohdana Zakharko 1 Ivanna Kernychna 3 Mariya Koval 4 Nataliia Hudz 5 Department of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine Department of Pharmacy, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine Department of Botany and Zoology, Volodymyr Hnatyuk Ternopil National Pedagogical University, Ternopil, Ukraine Department of General Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine Department of Pharmacy and Ecological Chemistry, University of Opole, Opole, Poland Department of Drug Technology and Biopharmacy, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine The genus Salvia L. (Sage) comprises over 900 species of aromatic and medicinal plants. Among the numerous sage species, Salvia officinalis and Salvia sclarea are well-known for their healing properties. This study aimed to analyze the morphological features and peculiarities of  the compositions of volatile compounds of Salvia nemorosa (cultivar ‘Ostfriesland’) and Salvia verbenaca cultivated in Ukraine, focusing on their chemotaxonomic characteristics.  Both representatives of the  Salvia genus were introduced in the Ternopil region of Ukraine, making them suitable for the further cultivation and harvesting under controlled conditions. The conducted gas chromatography-mass spectrometry (GC/MS) analysis revealed that the major volatile components of Salvia verbenaca were present in the following descending order: camphor (12.44%), eucalyptol (12.36%), α-pinene (11.45%), p-cymene (11.02%), camphene (5.64%), and (+)-3-carene (5.50%). In contrast, the predominant volatile compounds in Salvia nemorosa were found in such an order: β-caryophyllene (34.98%), caryophyllene oxide (18.92%), p-cymene (9.14%), and germacrene D (7.16%). Overall, monoterpenoids were among the dominant volatile compounds in Salvia verbenaca, while sesquiterpenoids were more prevalent in Salvia nemorosa. The findings of this study highlight the unique chemotaxonomic characteristics of the species examined and underscore their significant potential for further phytochemical and pharmacological research of  the leaves of both Salvia verbenaca and Salvia nemorosa. These plants may serve as valuable sources of bioactive molecules for the development of new medical herbal preparations  and functional food products. https://biomedpharmajournal.org/vol18no4/morphological-features-and-chemical-composition-of-volatile-compounds-of-cultivated-salvia-nemorosal-and-salvia-verbenaca-l/ Chemotaxonomic features Essential oil Ethnobotanical use Gas chromatography-mass spectrometry Medicinal plant Morphological characteristics Sage Terpenoids