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  <record>
    <language>eng</language>
          <publisher>Oriental Scientific Publishing Company</publisher>
        <journalTitle>Biomedical and Pharmacology Journal</journalTitle>
          <issn>0974-6242</issn>
            <publicationDate>2025-12-30</publicationDate>
    
        <volume>18</volume>
        <issue>4</issue>

 
    <startPage>2791</startPage>
    <endPage>2798</endPage>

	 
      <doi>10.13005/bpj/3294</doi>
        <publisherRecordId>68335</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Evaluation of Hemostatic and In vitro Antimicrobial Activity of (Revalum®) Feracrylum Gel</title>

    <authors>
	 


      <author>
       <name>Jayshree Dawane</name>

 
		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>Priti Dhande</name>


		
	<affiliationId>1</affiliationId>

      </author>
    

	 


      <author>
       <name>Bharati Dalal</name>

		
	<affiliationId>2</affiliationId>
      </author>
    

	


	


	
    </authors>
    
	    <affiliationsList>
	    
		
		<affiliationName affiliationId="1">Department of Pharmacology, Bharati Vidyapeeth DU Medical College, Pune, Maharashtra, India</affiliationName>
    

		
		<affiliationName affiliationId="2">Department of Microbiology, Bharati Vidyapeeth DU Medical College, Pune, Maharashtra, India </affiliationName>
    
		
		
		
		
	  </affiliationsList>






    <abstract language="eng">The study aims to evaluate the haemostatic and in vitro antimicrobial activity of Feracrylum gel Revalum<strong><sup> ®</sup></strong>, a novel topical formulation designed for wound management. An assessment was done to determine the haemostatic efficacy of the Feracrylum gel through standardized clotting assays, measuring its ability to promote bleeding control in both in-vitro and in-vivo models. The antimicrobial efficacy of the gel was assessed by testing its activity against a range of bacterial strains, encompassing both Gram-positive and Gram-negative bacteria, using the disk diffusion technique. The Feracrylum gel (Revalum)<strong><sup> ® </sup></strong>demonstrated significant hemostatic properties, with a marked reduction in bleeding time (p&lt;0.05) and clotting time (p&lt;0.001) compared to control treatments. In antimicrobial assays, the gel exhibited moderate antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus with 12mm, 10mm and 5mm zone of inhibition respectively. Feracrylum gel (Revalum)<strong><sup> ® </sup></strong>shows promising potential as an effective hemostatic agent and the gel demonstrates significant antimicrobial activity, indicating its potential for effective use in clinical wound care. Additional research is needed to evaluate its long-term efficacy and safety across various wound management scenarios.</abstract>

    <fullTextUrl format="html">https://biomedpharmajournal.org/vol18no4/evaluation-of-hemostatic-and-in-vitro-antimicrobial-activity-of-revalum-feracrylum-gel/</fullTextUrl>

<keywords language="eng">

      
        <keyword>Antimicrobial</keyword>
      

      
        <keyword> Feracrylum</keyword>
      

      
        <keyword> Haemostatic</keyword>
      

      
        <keyword> In-vitro</keyword>
      

      
        <keyword> Wound</keyword>
      
</keywords>
  </record>
</records>