eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-12-30 18 4 2741 2750 10.13005/bpj/3290 69463 article Sri Masyeni 1 Ratna Kartika Dewi 2 Kadek Suryawan 3 Saraswati Laksmi Dewi 1 Arya Giri Prebawa 1 Pande Ayu Naya Kasih Permatananda 2 Department of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa, Bali, Indonesia Faculty of Medicine and Health Sciences, Universitas Warmadewa, Bali, Indonesia Department of Microbiology, Faculty of Medicine and Health Sciences, Universitas Warmadewa, Bali, Indonesia Department of Infectious Disease and Immunology Research Center, Indonesia Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. The rising incidence of Streptococcus suis (S. suis)-associated meningitis, often associated with sudden deafness, warrants further investigation into its clinical characteristics and outcomes. This cross-sectional study analyzed medical records of patients with suspected S. suis-associated meningitis from 2022 to 2024, diagnosing the condition based on symptoms such as fever, headache, neck stiffness, and altered mental status, with confirmation via blood cultures. A notable limitation was the absence of CSF testing. Among 67 patients, 34 (50.7%) experienced deafness, although 3 had negative cultures. Key symptoms included fever (100%), neck stiffness (100%), and severe headache (28.4%). S. suis was identified in 10.5% of blood cultures, with 30 probable (44.8%) and seven confirmed cases (10.4%). Deafness occurred in 85.7% of S. suis bacteremia cases, but no significant link was found between raw pork consumption and deafness (p = 0.151). The overall case fatality rate was 4.5%, with a 1.5% mortality rate among confirmed cases. Common complications included septic shock and sudden deafness. Increased awareness and preventive measures related to pig exposure are essential to address this public health concern. https://biomedpharmajournal.org/vol18no4/detection-of-streptococcus-suis-bacteremia-in-a-subset-of-meningitis-patients-with-sudden-deafness/ Bacteremia Meningitis Sudden deafness S. Suis  Zoonotic