eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-12-30 18 4 2571 2584 10.13005/bpj/3277 68315 article Raju Thenge 1 Monali Ambuskar 1 Nishant Chopade 1 Karan Gayakwad 1 Aditya Bodade 1 Mohan Doijad 1 Department of Pharmaceutics, Dr. Rajendra Gode College of Pharmacy, Malkapur, Maharashtra, India. Human cancer therapy is a major issue in modern medical science. Lots of emerging materials are developing rapidly. Dendrimers, as a nanocarrier, are now widely used in the field biomedicine, pharmacy, and so on. As a super-branched macromolecule, dendrimers have a series of outstanding properties. Such as simple to functionalize, have nano & symmetric dimension and cavities for host-guest entrapment. It has made much progress in drug and gene delivery. Dendrimers have higher efficiency by perfecting the surface modification methods. The small molecules, DNAs, therapeutic agents, and more can be loaded into dendrimers. Also, the cytotoxicity is reducing gradually. dendrimers are promising drug delivery systems that can overcome the limitations associated with the currently used anticancer drugs. They have the capability to overcome drug resistance, reduce drug toxicity, improved the drug solubility and bioavailability. Different classes of anticancer drugs have been loaded into dendrimers, resulting in targeted drug delivery, sustained drug release mechanism, increased cellular uptake, reduced toxic side effects of the loaded drugs with enhanced anticancer activity in vitro and in vivo. https://biomedpharmajournal.org/vol18no4/dendrimer-in-cancer-treatment-a-review/ Application Characterization Dendrimer Evaluation Nanocarriers