eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-12-30 18 4 2751 2765 10.13005/bpj/3291 69246 article Wafaa Abdel Samie Kandeel 1 Ahmed Sayed Ismail 1 Mona Abdelkader Mohamed Awad 2 Eman Refaat Youness3 3 Hanaa Reyad Abdallah 1 Biological Anthropology Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt. Clinical and Chemical Pathology Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt. Medical biochemistry Department, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt. Vitamin D is increasingly recognized for its immunomodulatory and metabolic effects, with growing evidence linking deficiency to the development and progression of type 1 diabetes mellitus (T1DM).We aimed To evaluate vitamin D status among Egyptian T1D pediatric patients  and explore its relationship with glycemic control and body physique. A cross-sectional study was conducted on pediatric patients with T1DM. Serum 25-hydroxyvitamin D [25(OH)D] levels were assessed and categorized as deficient, insufficient, or sufficient. Clinical, anthropometric and biochemical parameters, including glycated hemoglobin (HbA1c), were assessed to determine associations with vitamin D status. Body composition was also analyzed. Vitamin D deficiency was highly prevalent, with the majority of patients demonstrating either deficient or insufficient levels. Lower VD levels were significantly associated with poorer glycemic control and higher BMI and body fat. There was no direct correlation between VD and HbA1c. We concluded that Vitamin D deficiency is common in Egyptian diabetic pediatric patients and is associated with adverse glycemic outcomes and higher BMI and body fat. Routine screening and appropriate supplementation may represent a valuable adjunct in disease management, although further future researches are required to confirm causality and establish evidence-based supplementation strategies. https://biomedpharmajournal.org/vol18no4/correlation-of-vitamin-d-level-with-body-physique-and-glycemic-control-in-type1-diabetic-egyptian-children-and-adolescents/ Adiposity Body composition Glycemic control Type 1 diabetes mellitus Vitamin D Vitamin D deficiency