eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-03-31 18 1 761 772 10.13005/bpj/3126 64554 article Prashanth Kumar Katta 1 Conservative Dentistry and Endodontics College of Dentistry, King Faisal University Al-Ahsa, Kingdom Of Saudi Arabia Purpose: to assess the adhesives' and low-viscosity bulk-fill composites' binding strength using 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP). Materials and Methods: iBOND by Kulzer, Prime&Bond elect by DENTSPLY Caulk, TOKUYAMA UNIVERSAL BOND II, Tokuyama Dental Corporation, and Adper Easy Bond Self-Etch Adhesive, as well as one 10-MDP-free adhesive (Xeno IV DC, Dentsply Sirona) were put on the air-abraded, polished outer layers of arbitrarily allocated Filtek™ Bulk Fill Flowable Restorative blocks. 3M™ Filtek™ Universal Restorative was then applied in layers after the adhesives. Using a hard-tissue microtome, each multilayer composite block was cut into stick specimens. Microtensile bond strength was measured on half of the groups (immediate group), while the remaining groups were matured in a thermocyling machine for 5000 cycles before having their microtensile bond strength tested (aged group). Scanning electron microscopy was used to assess the adhesive contact (SEM). Light microscopy was used to observe failure modes. Levene's test, ANOVA, Welch's ANOVA, Tukey's test, and the Z-test were used to analyze the results as necessary (significance: p 0.05). Results: The binding strength between the 10-MDP-containing adhesives and the 10-MDP-free glue varied significantly across all groups. In all glue groups, aging considerably reduced the binding strength. The binding strength and endurance of the 10-MDP-containing adhesives did not differ significantly from one another. Conclusion: Adhesives with 10-MDP outperform those without when applied to the air-abraded FiltekTM Bulk Fill Flowable Restorative composite surface. The chemical composition of the adhesives containing 10-MDP had no effect on the binding strength. As adhesives with 10-MDP age, their bond strength and durability declines. https://biomedpharmajournal.org/vol18no1/strength-of-bond-between-adhesives-and-low-viscosity-bulk-fill-composites-utilizing-10-methacryloyloxydecyl-dihydrogen-phosphate-10-mdp/ Aging Bond strength Low-viscosity bulk fill composite Self-etch bonding agents Universal bonding agents 10-MDP