eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-03-31 18 1 517 526 10.13005/bpj/3104 63700 article Adinarayana Andy 1 Ravindra Pukharaj Choudhary 2 Divya Andy 3 Srikanth Malavalli Siddalingegowda 2 Pharmacy Manager, Weatherwax Family Pharmacies Inc, Spring Arbor, Michigan, USA Department of Pharmacy Practice, JSS College of Pharmacy, Mysuru, Karnataka, India Independent Research consultant, Michigan, USA Obesity is a serious public health issue globally. Over the past three decades, many nations have experienced a substantial surge in obesity rates and obesity related non-communicable diseases (OR-NCDs), which has a considerable economic impact worldwide. It is estimated that more than 2.5 billion adults aged 18 and older were overweight, with over 890 million obese. Several anti-obesity medications came to market but were underutilized due to lack of safety evidence and concerns over adverse effects. Medication-induced weight gain is distressing for both patients and healthcare providers, and it can make it challenging to select and manage treatment regimens. Moreover, there has been a noticeable increase in preventable adverse drug events linked to medication-induced weight gain or obesity being reported to adverse drug reporting systems. Despite the availability of clinical care standards for obesity treatment and management, the outcomes have not been optimal. Hence, there is a need for a comprehensive and holistic approach that involves the proactive engagement of all the stakeholders involved in the care process. Clinical pharmacists are one among the key stakeholders in weight gain and obesity management, significantly contributing at various stages of patient care and in bariatric surgeries. Numerous studies have shown that clinical pharmacist-led weight management services and interventions have optimized treatment benefits. This paper emphasizes the need for and the role of clinical pharmacists in managing obesity. https://biomedpharmajournal.org/vol18no1/optimizing-weight-management-a-collaborative-strategy-with-clinical-pharmacists/ Anti-obesity medications Clinical pharmacy Drug-induced weight gain Obesity Weight-management