eng Oriental Scientific Publishing Company Biomedical and Pharmacology Journal 0974-6242 2025-03-31 18 1 559 568 10.13005/bpj/3108 65122 article Mariia Shanaida 1 Olha Korablova 2 Daryna Bakalets 1 Nataliya Potikha 3 Dzhamal Rakhmetov 2 Department of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine Department of Cultural Flora, M.M. Gryshko National Botanical Garden, National Academy of Sciences of Ukraine, Kyiv, Ukraine Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine The genus Savory (Satureja L.) from the Lamiaceae Martinov family contains several dozen species of aromatic plants. The scientific study of the chemical compounds and bioactivities varies significantly among the species within this genus. Certain species, such as Satureja montana L. and Satureja hortensis L., are particularly renowned for their healing properties. They are famous medicinal plants of world medicine. This study aimed to analyze the chromatographic profile of polyphenols and essential oil in the herb of blue savory (Satureja coerulea Janca) within its cultivation in Ukraine. Based on the results obtained, it was crucial to analyze the chemotaxonomic features of this species and identify the therapeutic potential of its bioactive compounds. The conducted GC/MS analysis indicated that the major components of the Satureja coerulea essential oil decreased in the following order: thymol (33.18%) > o-cymene (14.42%) > terpinen-4-ol (8.30%) > γ-terpinene (7.25%). The HPLC study identified the presence of 10 flavonoids and 9 phenolic acids. Among these, rosmarinic acid was found to be the most dominant phenolic acid, with a concentration of 13227.10 mg/kg. Regarding flavonoids, the highest concentrations were observed for luteolin-7-O-glucoside (7518.97 mg/kg) and apigenin-7-O-glucoside (3513.28 mg/kg). The findings of this study highlight the the unique chemotaxonomic characteristics of the studied species and its considerable potential for further pharmacological research of the essential oil and extract derived from the aerial part of Satureja coerulea. These substances may provide a source of various bioactive molecules for the pharmaceutical industry. https://biomedpharmajournal.org/vol18no1/chemotaxonomic-characteristics-of-saturejacoerulea-lamiaceae-family-based-on-analysis-of-its-bioactive-compounds/ Blue savory Chromatographic methods Endemic species Essential oil Flavonoids Medicinal plant of traditional medicine Phenolic acids Phytomedicine