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<records>

  <record>
    <language>eng</language>
          <publisher>Oriental Scientific Publishing Company</publisher>
        <journalTitle>Biomedical and Pharmacology Journal</journalTitle>
          <issn>0974-6242</issn>
            <publicationDate>2024-09-30</publicationDate>
    
        <volume>17</volume>
        <issue>3</issue>

 
    <startPage>1667</startPage>
    <endPage>1677</endPage>

	 
      <doi>10.13005/bpj/2974 </doi>
        <publisherRecordId>59904</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Formulation and Characteristics of Film Forming Hydrogel (FFH) of Yellow Root Extract (Arcangelisia Flava (L.) Merr.) As Wound Healing for Burns</title>

    <authors>
	 


      <author>
       <name>Rahmi Annisa</name>

 
		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>Yasmin Erly Agustin</name>


		
	<affiliationId>1</affiliationId>

      </author>
    

	 


      <author>
       <name>Nabila Rahmadani</name>

		
	<affiliationId>1</affiliationId>
      </author>
    

	 


      <author>
       <name>Roihatul Mutiah</name>

		
	<affiliationId>1</affiliationId>
      </author>
    


	


	
    </authors>
    
	    <affiliationsList>
	    
		
		<affiliationName affiliationId="1">Department of Pharmacy, Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim, Malang, Indonesia</affiliationName>
    

		
		
		
		
		
	  </affiliationsList>






    <abstract language="eng">The aim of this study was to determine the effect of different concentrations of yellow root extract (Arcangelisia Flava (L.) Merr.) and film-forming hydrogel (FFH) polymer on the physicochemical characteristics and stability of the preparation. The method for making FFH is carried out using varying concentrations (%) of 0,5 extract, 1, and 1,5, as well as variations in concentration (%) of PVP and PVA (2,8:15,2; 2,8:17,2; 2,8:19,2). F1 – F9 were evaluated for physicochemical characteristics, including organoleptic, pH, spreadability, adhesive power, drying time, viscosity, stickiness, and mechanical properties. Next, freeze-thaw stability and data analysis were carried out using the LSD test at a confidence level of 95%. This research indicates that the FFH formulation of yellow root extract has good characteristics in the F1 formula with an extract concentration of 0.5% and a concentration (%) of PVP and PVP polymer (2.8:15.2), which meets all physicochemical characteristic tests. The results of data analysis using SPSS showed that the extract concentration and polymer concentration had a significant effect (0.05&lt;0.05) on the characteristics and stability of the Yellow Root Extract Film Forming Hydrogel (FFH) preparation.</abstract>

    <fullTextUrl format="html">https://biomedpharmajournal.org/vol17no3/formulation-and-characteristics-of-film-forming-hydrogel-ffh-of-yellow-root-extract-arcangelisia-flava-l-merr-as-wound-healing-for-burns/</fullTextUrl>

<keywords language="eng">

      
        <keyword>Burns</keyword>
      

      
        <keyword> Film Forming Hydrogel</keyword>
      

      
        <keyword> Polymers</keyword>
      

      
        <keyword> Wound</keyword>
      

      
        <keyword> Yellow Root Extract</keyword>
      
</keywords>
  </record>
</records>